Explore MGP gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the osteocalcin/matrix Gla family of proteins. The encoded vitamin K-dependent protein is secreted by chondrocytes and vascular smooth muscle cells, and functions as a physiological inhibitor of ectopic tissue calcification. Carboxylation status of the encoded protein is associated with calcification of the vasculature in human patients with cardiovascular disease and calcification of the synovial membranes in osteoarthritis patients. Mutations in this gene cause Keutel syndrome in human patients, which is characterized by abnormal cartilage calcification, peripheral pulmonary stenosis and facial hypoplasia. [provided by RefSeq, Sep 2016]
| Target ID |
GM-SE1099
|
| Target Name |
MGP
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
4256
|
| Gene ID |
100063934 (Equus caballus), 100856382 (Canis lupus familiaris), 101096741 (Felis catus), 17313 (Mus musculus) 25333 (Rattus norvegicus), 282660 (Bos taurus), 4256 (Homo sapiens), 574116 (Macaca mulatta)
|
| Target Alternative Names |
Cell growth-inhibiting gene 36 protein,GIG36,MGLAP,MGP,Matrix Gla protein,Mglap,Mgp,NTI
|
| Uniprot Accession |
P19788,P08494,P07507,P08493
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Gene Ensembl |
ENSCAFG00845021156, ENSMUSG00000030218, ENSG00000111341, ENSMMUG00000047247
|
Pre-made viral vector of MGP cDNA Clones/ORF Plasmid
MGP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4256 | Pre-made Human MGP/NTI/GIG36 siRNA oligo Duplex | 4256 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25333 | Pre-made Rat Mgp/Mglap siRNA oligo Duplex | 25333 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17313 | Pre-made Mouse Mgp/Mglap siRNA oligo Duplex | 17313 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574116 | Pre-made Cynomolgus/Rhesus macaque MGP siRNA oligo Duplex | 574116 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101096741 | Pre-made Cat/Feline MGP siRNA oligo Duplex | 101096741 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100856382 | Pre-made Dog/Canine MGP siRNA oligo Duplex | 100856382 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282660 | Pre-made Bovines/Cattle MGP siRNA oligo Duplex | 282660 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100063934 | Pre-made Equine/Horse MGP siRNA oligo Duplex | 100063934 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MGP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1099-Ab | Human | Anti-Human MGP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1099-Ab | Rat | Anti-Rat MGP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1099-Ab | Mouse | Anti-Mouse MGP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1099-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MGP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1099-Ab | Cat/Feline | Anti-Cat/Feline MGP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1099-Ab | Dog/Canine | Anti-Dog/Canine MGP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE1099-Ab | Bovines/Cattle | Anti-Bovines/Cattle MGP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1099-Ab | Equine/Horse | Anti-Equine/Horse MGP monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
MGP recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1099-Ag | Human | Human MGP recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1099-Ag | Rat | Rat MGP recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1099-Ag | Mouse | Mouse MGP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1099-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MGP recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1099-Ag | Cat/Feline | Cat/Feline MGP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1099-Ag | Dog/Canine | Dog/Canine MGP recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1099-Ag | Bovines/Cattle | Bovines/Cattle MGP recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1099-Ag | Equine/Horse | Equine/Horse MGP recombinant protein | Mammalian cell | Detail |