Recombinant multi-species MGP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MGP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the osteocalcin/matrix Gla family of proteins. The encoded vitamin K-dependent protein is secreted by chondrocytes and vascular smooth muscle cells, and functions as a physiological inhibitor of ectopic tissue calcification. Carboxylation status of the encoded protein is associated with calcification of the vasculature in human patients with cardiovascular disease and calcification of the synovial membranes in osteoarthritis patients. Mutations in this gene cause Keutel syndrome in human patients, which is characterized by abnormal cartilage calcification, peripheral pulmonary stenosis and facial hypoplasia. [provided by RefSeq, Sep 2016]
The Alternative Names of target: Cell growth-inhibiting gene 36 protein,GIG36,MGLAP,MGP,Matrix Gla protein,Mglap,Mgp,NTI

Target products collectionGo to MGP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE1099-Ag-1/ GM-Tg-hg-SE1099-Ag-2 Human MGP protein Human
GM-Tg-rg-SE1099-Ag-1/ GM-Tg-rg-SE1099-Ag-2 Rat MGP protein Rat
GM-Tg-mg-SE1099-Ag-1/ GM-Tg-mg-SE1099-Ag-2 Mouse MGP protein Mouse
GM-Tg-cynog-SE1099-Ag-1/ GM-Tg-cynog-SE1099-Ag-2 Cynomolgus/Rhesus macaque MGP protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE1099-Ag-1/ GM-Tg-felg-SE1099-Ag-2 Feline MGP protein Feline
GM-Tg-cang-SE1099-Ag-1/ GM-Tg-cang-SE1099-Ag-2 Canine MGP protein Canine
GM-Tg-bovg-SE1099-Ag-1/ GM-Tg-bovg-SE1099-Ag-2 Bovine MGP protein Bovine
GM-Tg-equg-SE1099-Ag-1/ GM-Tg-equg-SE1099-Ag-2 Equine MGP protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE1099-Ag-1/ GM-Tg-hg-SE1099-Ag-2; GM-Tg-rg-SE1099-Ag-1/ GM-Tg-rg-SE1099-Ag-2;
GM-Tg-mg-SE1099-Ag-1/ GM-Tg-mg-SE1099-Ag-2; GM-Tg-cynog-SE1099-Ag-1/ GM-Tg-cynog-SE1099-Ag-2;
GM-Tg-felg-SE1099-Ag-1/ GM-Tg-felg-SE1099-Ag-2; GM-Tg-cang-SE1099-Ag-1/ GM-Tg-cang-SE1099-Ag-2;
GM-Tg-bovg-SE1099-Ag-1/ GM-Tg-bovg-SE1099-Ag-2; GM-Tg-equg-SE1099-Ag-1/ GM-Tg-equg-SE1099-Ag-2
Products Name MGP protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name MGP
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MGP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.