Explore IL-27/IL-27A/IL27 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR). [provided by RefSeq, Jul 2008]
| Target ID |
GM-SE1026
|
| Target Name |
IL-27/IL-27A/IL27
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
246778
|
| Gene ID |
100066317 (Equus caballus), 101093822 (Felis catus), 246778 (Homo sapiens), 246779 (Mus musculus)
365368 (Rattus norvegicus), 607880 (Canis lupus familiaris), 614927 (Bos taurus), 708678 (Macaca mulatta)
|
| Target Alternative Names |
IL-27,IL-27 subunit alpha,IL-27-A,IL-27A,IL-27alpha,IL-27p28,IL27,IL27-A,IL27A,IL27p28,IL30,Il27,Il30,Interleukin-27 subunit alpha,Interleukin-30,RGD1561420,p28
|
| Uniprot Accession |
Q8NEV9,Q8K3I6
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Th17 cell differentiation
|
| Gene Ensembl |
ENSECAG00000014957, ENSG00000197272, ENSMUSG00000044701, ENSCAFG00845002305, ENSBTAG00000018015, ENSMMUG00000045351
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of IL-27/IL-27A/IL27 cDNA Clones/ORF Plasmid
IL-27/IL-27A/IL27 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo246778 | Pre-made Human IL27/p28/IL30 siRNA oligo Duplex | 246778 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo365368 | Pre-made Rat Il27/RGD1561420 siRNA oligo Duplex | 365368 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo246779 | Pre-made Mouse Il27/p28/Il30 siRNA oligo Duplex | 246779 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo708678 | Pre-made Cynomolgus/Rhesus macaque IL27/IL-27alpha siRNA oligo Duplex | 708678 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093822 | Pre-made Cat/Feline IL27 siRNA oligo Duplex | 101093822 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo607880 | Pre-made Dog/Canine IL27 siRNA oligo Duplex | 607880 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo614927 | Pre-made Bovines/Cattle IL27 siRNA oligo Duplex | 614927 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100066317 | Pre-made Equine/Horse IL27 siRNA oligo Duplex | 100066317 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-27/IL-27A/IL27 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE1026-Ab | Human | Anti-Human IL-27/IL-27A/IL27 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-SE1026-Ab | Rat | Anti-Rat IL-27/IL-27A/IL27 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-SE1026-Ab | Mouse | Anti-Mouse IL-27/IL-27A/IL27 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-SE1026-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-27/IL-27A/IL27 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-SE1026-Ab | Cat/Feline | Anti-Cat/Feline IL-27/IL-27A/IL27 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-SE1026-Ab | Dog/Canine | Anti-Dog/Canine IL-27/IL-27A/IL27 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-SE1026-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-27/IL-27A/IL27 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-SE1026-Ab | Equine/Horse | Anti-Equine/Horse IL-27/IL-27A/IL27 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
IL-27/IL-27A/IL27 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE1026-Ag | Human | Human IL-27/IL-27A/IL27 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-SE1026-Ag | Rat | Rat IL-27/IL-27A/IL27 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-SE1026-Ag | Mouse | Mouse IL-27/IL-27A/IL27 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE1026-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-27/IL-27A/IL27 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE1026-Ag | Cat/Feline | Cat/Feline IL-27/IL-27A/IL27 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-SE1026-Ag | Dog/Canine | Dog/Canine IL-27/IL-27A/IL27 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE1026-Ag | Bovines/Cattle | Bovines/Cattle IL-27/IL-27A/IL27 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE1026-Ag | Equine/Horse | Equine/Horse IL-27/IL-27A/IL27 recombinant protein | Mammalian cell | Detail |
