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Target
sublocation: Secreted Protein/Potential Cytokines.
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq, Sep 2014]
| Target ID |
GM-SE0751
|
| Target Name |
CCL8
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6355
|
| Gene ID |
100033927 (Equus caballus), 101097189 (Felis catus), 574179 (Macaca mulatta), 6355 (Homo sapiens)
|
| Target Alternative Names |
CCL8,mcp-2,HC14,MCP2,MCP-2,SCYA8,SCYA10
|
| Uniprot Accession |
P80075
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease |
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway
|
| Gene Ensembl |
ENSECAG00000034282, ENSMMUG00000009784, ENSG00000108700
|
| Target Classification |
|
Pre-made viral vector of CCL8 cDNA Clones/ORF Plasmid
CCL8 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6355 | Pre-made Human CCL8/HC14/MCP2 siRNA oligo Duplex | 6355 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo574179 | Pre-made Cynomolgus/Rhesus macaque CCL8 siRNA oligo Duplex | 574179 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101097189 | Pre-made Cat/Feline CCL8 siRNA oligo Duplex | 101097189 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100033927 | Pre-made Equine/Horse CCL8/mcp-2 siRNA oligo Duplex | 100033927 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CCL8 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0751-Ab | Human | Anti-Human CCL8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0751-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CCL8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE0751-Ab | Cat/Feline | Anti-Cat/Feline CCL8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0751-Ab | Equine/Horse | Anti-Equine/Horse CCL8 monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
CCL8 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0751-Ag | Human | Human CCL8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0751-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CCL8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0751-Ag | Cat/Feline | Cat/Feline CCL8 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0751-Ag | Equine/Horse | Equine/Horse CCL8 recombinant protein | Mammalian cell | Detail |
