Recombinant multi-species CCL8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCL8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq, Sep 2014]
The Alternative Names of target: CCL8,C-C motif chemokine 8,HC14, Monocyte chemoattractant protein 2, Monocyte chemotactic protein 2 (MCP-2), Small-inducible cytokine A8,HC14,MCP2,MCP-2,SCYA8,SCYA10

Target products collectionGo to CCL8 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-SE0751-Ab-1/ GM-Tg-hg-SE0751-Ab-2 Human CCL8 protein Human
GM-Tg-rg-SE0751-Ab-1/ GM-Tg-rg-SE0751-Ab-2 Rat CCL8 protein Rat
GM-Tg-mg-SE0751-Ab-1/ GM-Tg-mg-SE0751-Ab-2 Mouse CCL8 protein Mouse
GM-Tg-cynog-SE0751-Ab-1/ GM-Tg-cynog-SE0751-Ab-2 Cynomolgus/Rhesus macaque CCL8 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-SE0751-Ab-1/ GM-Tg-felg-SE0751-Ab-2 Feline CCL8 protein Feline
GM-Tg-cang-SE0751-Ab-1/ GM-Tg-cang-SE0751-Ab-2 Canine CCL8 protein Canine
GM-Tg-bovg-SE0751-Ab-1/ GM-Tg-bovg-SE0751-Ab-2 Bovine CCL8 protein Bovine
GM-Tg-equg-SE0751-Ab-1/ GM-Tg-equg-SE0751-Ab-2 Equine CCL8 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-SE0751-Ab-1/ GM-Tg-hg-SE0751-Ab-2; GM-Tg-rg-SE0751-Ab-1/ GM-Tg-rg-SE0751-Ab-2;
GM-Tg-mg-SE0751-Ab-1/ GM-Tg-mg-SE0751-Ab-2; GM-Tg-cynog-SE0751-Ab-1/ GM-Tg-cynog-SE0751-Ab-2;
GM-Tg-felg-SE0751-Ab-1/ GM-Tg-felg-SE0751-Ab-2; GM-Tg-cang-SE0751-Ab-1/ GM-Tg-cang-SE0751-Ab-2;
GM-Tg-bovg-SE0751-Ab-1/ GM-Tg-bovg-SE0751-Ab-2; GM-Tg-equg-SE0751-Ab-1/ GM-Tg-equg-SE0751-Ab-2
Products Name CCL8 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CCL8
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCL8 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.