Recombinant multi-species CCL8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCL8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq, Sep 2014]
The Alternative Names of target: CCL8,C-C motif chemokine 8,HC14, Monocyte chemoattractant protein 2, Monocyte chemotactic protein 2 (MCP-2), Small-inducible cytokine A8,HC14,MCP2,MCP-2,SCYA8,SCYA10
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Product information
Catalog No. | Product Name | Species Reactivity |
---|---|---|
GM-Tg-hg-SE0751-Ab-1/ GM-Tg-hg-SE0751-Ab-2 | Human CCL8 protein | Human |
GM-Tg-rg-SE0751-Ab-1/ GM-Tg-rg-SE0751-Ab-2 | Rat CCL8 protein | Rat |
GM-Tg-mg-SE0751-Ab-1/ GM-Tg-mg-SE0751-Ab-2 | Mouse CCL8 protein | Mouse |
GM-Tg-cynog-SE0751-Ab-1/ GM-Tg-cynog-SE0751-Ab-2 | Cynomolgus/Rhesus macaque CCL8 monoclonal antibody | Cynomolgus/ Rhesus macaque |
GM-Tg-felg-SE0751-Ab-1/ GM-Tg-felg-SE0751-Ab-2 | Feline CCL8 protein | Feline |
GM-Tg-cang-SE0751-Ab-1/ GM-Tg-cang-SE0751-Ab-2 | Canine CCL8 protein | Canine |
GM-Tg-bovg-SE0751-Ab-1/ GM-Tg-bovg-SE0751-Ab-2 | Bovine CCL8 protein | Bovine |
GM-Tg-equg-SE0751-Ab-1/ GM-Tg-equg-SE0751-Ab-2 | Equine CCL8 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
Catalog No. |
GM-Tg-hg-SE0751-Ab-1/ GM-Tg-hg-SE0751-Ab-2;
GM-Tg-rg-SE0751-Ab-1/ GM-Tg-rg-SE0751-Ab-2;
GM-Tg-mg-SE0751-Ab-1/ GM-Tg-mg-SE0751-Ab-2; GM-Tg-cynog-SE0751-Ab-1/ GM-Tg-cynog-SE0751-Ab-2; GM-Tg-felg-SE0751-Ab-1/ GM-Tg-felg-SE0751-Ab-2; GM-Tg-cang-SE0751-Ab-1/ GM-Tg-cang-SE0751-Ab-2; GM-Tg-bovg-SE0751-Ab-1/ GM-Tg-bovg-SE0751-Ab-2; GM-Tg-equg-SE0751-Ab-1/ GM-Tg-equg-SE0751-Ab-2 |
Products Name | CCL8 protein |
Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
Target Name | CCL8 |
Protein Sub-location | Secreted Protein/Potential Cytokines |
Isotypes | Recombinant protein |
Expression platform | Mammalian cell |
Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
Tag | His |
Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCL8 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab
GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.