Explore NAP2/PPBP gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. [provided by RefSeq, Nov 2014]
| Target ID |
GM-SE0421
|
| Target Name |
NAP2/PPBP
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5473
|
| Gene ID |
100055973 (Equus caballus), 101094344 (Felis catus), 5473 (Homo sapiens), 613723 (Bos taurus)
703334 (Macaca mulatta)
|
| Target Alternative Names |
B-TG1,Beta-TG,C-X-C motif chemokine 7,CTAP-III,CTAP3,CTAPIII,CXCL7,LA-PF4,LDGF,Leukocyte-derived growth factor (LDGF),MDGF,Macrophage-derived growth factor (MDGF),NAP-2,NAP2,PBP,PPBP,Platelet basic protein,SCYB7,Small-inducible cytokine B7,TC1,TC2,TGB,TGB1,THBGB,THBGB1
|
| Uniprot Accession |
P02775
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Cytokine Target
|
| Disease |
Ovary Cancer, Sepsis, Dent disease, Diabetes type-2
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor, Chemokine signaling pathway
|
| Gene Ensembl |
ENSECAG00000012702, ENSG00000163736, ENSBTAG00000011961, ENSMMUG00000042371
|
Pre-made viral vector of NAP2/PPBP cDNA Clones/ORF Plasmid
NAP2/PPBP siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5473 | Pre-made Human PPBP/PBP/TC1 siRNA oligo Duplex | 5473 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo703334 | Pre-made Cynomolgus/Rhesus macaque PPBP siRNA oligo Duplex | 703334 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094344 | Pre-made Cat/Feline PPBP siRNA oligo Duplex | 101094344 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo613723 | Pre-made Bovines/Cattle PPBP siRNA oligo Duplex | 613723 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100055973 | Pre-made Equine/Horse PPBP siRNA oligo Duplex | 100055973 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
NAP2/PPBP antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-SE0421-Ab | Human | Anti-Human NAP2/PPBP monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-SE0421-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque NAP2/PPBP monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-felg-SE0421-Ab | Cat/Feline | Anti-Cat/Feline NAP2/PPBP monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-SE0421-Ab | Bovines/Cattle | Anti-Bovines/Cattle NAP2/PPBP monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-SE0421-Ab | Equine/Horse | Anti-Equine/Horse NAP2/PPBP monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
NAP2/PPBP recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-SE0421-Ag | Human | Human NAP2/PPBP recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-SE0421-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque NAP2/PPBP recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-SE0421-Ag | Cat/Feline | Cat/Feline NAP2/PPBP recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-SE0421-Ag | Bovines/Cattle | Bovines/Cattle NAP2/PPBP recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-SE0421-Ag | Equine/Horse | Equine/Horse NAP2/PPBP recombinant protein | Mammalian cell | Detail |
