Recombinant multi-species NAP2/PPBP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NAP2/PPBP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. The protein also is an antimicrobial protein with bactericidal and antifungal activity. [provided by RefSeq, Nov 2014]
The Alternative Names of target: B-TG1,Beta-TG,C-X-C motif chemokine 7,CTAP-III,CTAP3,CTAPIII,CXCL7,LA-PF4,LDGF,Leukocyte-derived growth factor (LDGF),MDGF,Macrophage-derived growth factor (MDGF),NAP-2,NAP2,PBP,PPBP,Platelet basic protein,SCYB7,Small-inducible cytokine B7,TC1,TC2,TGB,TGB1,THBGB,THBGB1
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-SE0421-Ag-1/ GM-Tg-hg-SE0421-Ag-2 | Human NAP2/PPBP protein | Human |
| GM-Tg-rg-SE0421-Ag-1/ GM-Tg-rg-SE0421-Ag-2 | Rat NAP2/PPBP protein | Rat |
| GM-Tg-mg-SE0421-Ag-1/ GM-Tg-mg-SE0421-Ag-2 | Mouse NAP2/PPBP protein | Mouse |
| GM-Tg-cynog-SE0421-Ag-1/ GM-Tg-cynog-SE0421-Ag-2 | Cynomolgus/Rhesus macaque NAP2/PPBP protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-SE0421-Ag-1/ GM-Tg-felg-SE0421-Ag-2 | Feline NAP2/PPBP protein | Feline |
| GM-Tg-cang-SE0421-Ag-1/ GM-Tg-cang-SE0421-Ag-2 | Canine NAP2/PPBP protein | Canine |
| GM-Tg-bovg-SE0421-Ag-1/ GM-Tg-bovg-SE0421-Ag-2 | Bovine NAP2/PPBP protein | Bovine |
| GM-Tg-equg-SE0421-Ag-1/ GM-Tg-equg-SE0421-Ag-2 | Equine NAP2/PPBP protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-SE0421-Ag-1/ GM-Tg-hg-SE0421-Ag-2;
GM-Tg-rg-SE0421-Ag-1/ GM-Tg-rg-SE0421-Ag-2;
GM-Tg-mg-SE0421-Ag-1/ GM-Tg-mg-SE0421-Ag-2; GM-Tg-cynog-SE0421-Ag-1/ GM-Tg-cynog-SE0421-Ag-2; GM-Tg-felg-SE0421-Ag-1/ GM-Tg-felg-SE0421-Ag-2; GM-Tg-cang-SE0421-Ag-1/ GM-Tg-cang-SE0421-Ag-2; GM-Tg-bovg-SE0421-Ag-1/ GM-Tg-bovg-SE0421-Ag-2; GM-Tg-equg-SE0421-Ag-1/ GM-Tg-equg-SE0421-Ag-2 |
| Products Name | NAP2/PPBP protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | NAP2/PPBP |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NAP2/PPBP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
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Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.