Explore IL-1RA/IL1RN gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses, particularly in the acute phase of infection and inflammation. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Aug 2020]
| Target ID |
GM-MP2544
|
| Target Name |
IL-1RA/IL1RN
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3557
|
| Gene ID |
100034236 (Equus caballus), 16181 (Mus musculus), 281860 (Bos taurus), 3557 (Homo sapiens)
403660 (Canis lupus familiaris), 60582 (Rattus norvegicus), 701658 (Macaca mulatta)
|
| Target Alternative Names |
CRMO2,DIRA,F630041P17Rik,ICIL-1RA,IL-1RA,IL-1RN,IL-1ra,IL-1ra3,IL1 inhibitor,IL1F3,IL1RA,IL1RN,IRAP,Il1ra,Il1rn,Interleukin-1 receptor antagonist protein,MVCD4
|
| Uniprot Accession |
O18999,P25085,O77482,P18510,Q9BEH0,P25086
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction
|
| Gene Ensembl |
ENSMUSG00000026981, ENSBTAG00000019665, ENSG00000136689, ENSCAFG00845011971, ENSMMUG00000013014
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of IL-1RA/IL1RN cDNA Clones/ORF Plasmid
IL-1RA/IL1RN siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3557 | Pre-made Human IL1RN/DIRA/IRAP siRNA oligo Duplex | 3557 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo60582 | Pre-made Rat Il1rn/Il1ra/IL-1ra siRNA oligo Duplex | 60582 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo16181 | Pre-made Mouse Il1rn/IL-1ra/F630041P17Rik siRNA oligo Duplex | 16181 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo701658 | Pre-made Cynomolgus/Rhesus macaque IL1RN siRNA oligo Duplex | 701658 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403660 | Pre-made Dog/Canine IL1RN/IL-1ra siRNA oligo Duplex | 403660 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281860 | Pre-made Bovines/Cattle IL1RN siRNA oligo Duplex | 281860 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034236 | Pre-made Equine/Horse IL1RN/IL-1RA siRNA oligo Duplex | 100034236 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
IL-1RA/IL1RN antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP2544-Ab | Human | Anti-Human IL-1RA/IL1RN monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-rg-MP2544-Ab | Rat | Anti-Rat IL-1RA/IL1RN monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-mg-MP2544-Ab | Mouse | Anti-Mouse IL-1RA/IL1RN monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-MP2544-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque IL-1RA/IL1RN monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-cang-MP2544-Ab | Dog/Canine | Anti-Dog/Canine IL-1RA/IL1RN monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-bovg-MP2544-Ab | Bovines/Cattle | Anti-Bovines/Cattle IL-1RA/IL1RN monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
| GM-Tg-equg-MP2544-Ab | Equine/Horse | Anti-Equine/Horse IL-1RA/IL1RN monoclonal antibody | mab | FACS/Biofunctional Antibody, Cytokine antibody | Detail |
IL-1RA/IL1RN VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP2544-Ag | Human | Human IL-1RA/IL1RN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP2544-Ag | Rat | Rat IL-1RA/IL1RN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP2544-Ag | Mouse | Mouse IL-1RA/IL1RN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP2544-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque IL-1RA/IL1RN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP2544-Ag | Dog/Canine | Dog/Canine IL-1RA/IL1RN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP2544-Ag | Bovines/Cattle | Bovines/Cattle IL-1RA/IL1RN VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP2544-Ag | Equine/Horse | Equine/Horse IL-1RA/IL1RN VLP (virus-like particle) | HEK293 | Products Developing |
