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Human IL1RN/ICIL-1RA/IL-1ra3 ORF/cDNA clone-Adenovirus particle (BC009745)
Cat. No.: vGMAP000045
Pre-made Human IL1RN/ICIL-1RA/IL-1ra3 Adenovirus for IL1RN overexpression in-vitro and in-vivo. The IL1RN adenoviral vector excels as a vehicle for transient gene transfection in both stable cell lines and primary cells, including DC cells, macrophages, cardiomyocytes, hepatocytes, and neurons. The purified IL1RN-encoding adenovirus also stands out as a quintessential tool for in vivo studies and vaccine research initiatives.
At GM Vector Core (GMVC), we provide bespoke adenovirus development and manufacture various grades of adenoviruses utilizing cutting-edge techniques. Dive deeper into our offerings.
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IL-1RA/IL1RN/IL1RN/ICIL-1RA products
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Product information
| Catalog No. | Product Name | Adenovirus Grade | Adenovirus quantity |
| vGMAP000045 | Human IL1RN Adenovirus particle | Research Grade-In vitro | 1E+10PFU (1E+10pfu/ml×1ml) |
| 5E+10PFU (1E+10pfu/ml×5ml) | |||
| 1E+11PFU (1E+10pfu/ml×10ml) | |||
| Research Grade-In vivo | 1E+11PFU (1E+11pfu/ml×1ml) | ||
| GMP-like Grade | inquiry | ||
| GMP Grade | inquiry |
Product Description
| Catalog ID | vGMAP000045 |
| Gene Name | IL1RN |
| Accession Number | BC009745 |
| Gene ID | 3557 |
| Species | Human |
| Product Type | Adenovirus particle (overexpression) |
| Insert Length | 480 bp |
| Gene Alias | ICIL-1RA,IL-1ra3,IL1F3,IL1RA,IRAP,MGC10430 |
| Fluorescent Reporter | GFP |
| Mammalian Cell Selection | Null |
| Fusion Tag | 3xflag (C-Terminal) |
| Promoter | EF1 |
| Resistance | Kanamycin |
| ORF Nucleotide Sequence | ATGGCTTTAGAGACGATCTGCCGACCCTCTGGGAGAAAATCCAGCAAGATGCAAGCCTTCAGAATCTGGGATGTTAACCAGAAGACCTTCTATCTGAGGAACAACCAACTAGTTGCCGGATACTTGCAAGGACCAAATGTCAATTTAGAAGAAAAGATAGATGTGGTACCCATTGAGCCTCATGCTCTGTTCTTGGGAATCCATGGAGGGAAGATGTGCCTGTCCTGTGTCAAGTCTGGTGATGAGACCAGACTCCAGCTGGAGGCAGTTAACATCACTGACCTGAGCGAGAACAGAAAGCAGGACAAGCGCTTCGCCTTCATCCGCTCAGACAGTGGCCCCACCACCAGTTTTGAGTCTGCCGCCTGCCCCGGTTGGTTCCTCTGCACAGCGATGGAAGCTGACCAGCCCGTCAGCCTCACCAATATGCCTGACGAAGGCGTCATGGTCACCAAATTCTACTTCCAGGAGGACGAGTAG |
| ORF Protein Sequence | MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE |
Reference
Data / case study
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Associated products
| Category | Cat No. | Products Name |
|---|---|---|
| Target Antibody | GM-Tg-g-MP2544-Ab | Anti-IL1RA/ IL1RN/ DIRA monoclonal antibody |
| Target Antigen | GM-Tg-g-MP2544-Ag | IL1RN VLP (virus-like particle) |
| Cytokine | cks-Tg-g-GM-MP2544 | interleukin 1 receptor antagonist (IL1RN) protein & antibody |
| ORF Viral Vector | pGMLP000397 | Human IL1RN Lentivirus plasmid |
| ORF Viral Vector | pGMAP000045 | Human IL1RN Adenovirus plasmid |
| ORF Viral Vector | pGMLP-IL-004 | Human IL1RN Lentivirus plasmid |
| ORF Viral Vector | pGMAP-IL-087 | Human IL1RN Adenovirus plasmid |
| ORF Viral Vector | vGMLP000397 | Human IL1RN Lentivirus particle |
| ORF Viral Vector | vGMAP000045 | Human IL1RN Adenovirus particle |
| ORF Viral Vector | vGMLP-IL-004 | Human IL1RN Lentivirus particle |
| ORF Viral Vector | vGMAP-IL-087 | Human IL1RN Adenovirus particle |
Target information
| Target ID | GM-MP2544 |
| Target Name | IL-1RA/IL1RN |
|
Gene Group Identifier （Target Gene ID in Homo species) |
3557 |
| Gene ID |
100034236 (Equus caballus), 16181 (Mus musculus), 281860 (Bos taurus), 3557 (Homo sapiens) 403660 (Canis lupus familiaris), 60582 (Rattus norvegicus), 701658 (Macaca mulatta) |
| Gene Symbols & Synonyms | IL1RN,Il1rn,IL-1RA,IL-1ra,F630041P17Rik,DIRA,IRAP,CRMO2,IL1F3,IL1RA,MVCD4,IL-1RN,IL-1ra3,ICIL-1RA,Il1ra |
| Target Alternative Names | CRMO2,DIRA,F630041P17Rik,ICIL-1RA,IL-1RA,IL-1RN,IL-1ra,IL-1ra3,IL1 inhibitor,IL1F3,IL1RA,IL1RN,IRAP,Il1ra,Il1rn,Interleukin-1 receptor antagonist protein,MVCD4 |
| Uniprot Accession |
O18999,O77482,P18510,P25085,P25086,Q9BEH0
Additional SwissProt Accessions: O18999,P25085,O77482,P18510,Q9BEH0,P25086 |
| Uniprot Entry Name | |
| Protein Sub-location | Transmembrane Protein |
| Category | Cytokine Target |
| Disease | cancer |
| Disease from KEGG | Cytokine-cytokine receptor interaction |
| Gene Ensembl | ENSMUSG00000026981, ENSBTAG00000019665, ENSG00000136689, ENSCAFG00845011971, ENSMMUG00000013014 |
| Target Classification | Tumor-associated antigen (TAA) |
About GMVC
GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.