Explore Claudin 1/CLDN1 gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0271
|
| Target Name |
Claudin 1/CLDN1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
9076
|
| Gene ID |
100059811 (Equus caballus), 101094619 (Felis catus), 12737 (Mus musculus), 414922 (Bos taurus)
608207 (Canis lupus familiaris), 65129 (Rattus norvegicus), 704330 (Macaca mulatta), 9076 (Homo sapiens)
|
| Target Alternative Names |
CLD1,CLDN1,Claudin 1,Claudin-1,Cldn1,ILVASC,SEMP1,Senescence-associated epithelial membrane protein,claudin-1
|
| Uniprot Accession |
O88551,Q6L708,P56745,O95832
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Cell adhesion molecules, Tight junction, Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Hepatitis C
|
| Gene Ensembl |
ENSECAG00000021074, ENSMUSG00000022512, ENSBTAG00000013148, ENSCAFG00845024289, ENSMMUG00000001915, ENSG00000163347
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of Claudin 1/CLDN1 cDNA Clones/ORF Plasmid
Claudin 1/CLDN1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo9076 | Pre-made Human CLDN1/CLD1/SEMP1 siRNA oligo Duplex | 9076 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo65129 | Pre-made Rat Cldn1 siRNA oligo Duplex | 65129 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12737 | Pre-made Mouse Cldn1 siRNA oligo Duplex | 12737 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo704330 | Pre-made Cynomolgus/Rhesus macaque CLDN1/claudin-1 siRNA oligo Duplex | 704330 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094619 | Pre-made Cat/Feline CLDN1 siRNA oligo Duplex | 101094619 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo608207 | Pre-made Dog/Canine CLDN1 siRNA oligo Duplex | 608207 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo414922 | Pre-made Bovines/Cattle CLDN1 siRNA oligo Duplex | 414922 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059811 | Pre-made Equine/Horse CLDN1 siRNA oligo Duplex | 100059811 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
Claudin 1/CLDN1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0271-Ab | Human | Anti-Human Claudin 1/CLDN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0271-Ab | Rat | Anti-Rat Claudin 1/CLDN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0271-Ab | Mouse | Anti-Mouse Claudin 1/CLDN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0271-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque Claudin 1/CLDN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0271-Ab | Cat/Feline | Anti-Cat/Feline Claudin 1/CLDN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0271-Ab | Dog/Canine | Anti-Dog/Canine Claudin 1/CLDN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0271-Ab | Bovines/Cattle | Anti-Bovines/Cattle Claudin 1/CLDN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0271-Ab | Equine/Horse | Anti-Equine/Horse Claudin 1/CLDN1 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
Claudin 1/CLDN1 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0271-Ag | Human | Human Claudin 1/CLDN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0271-Ag | Rat | Rat Claudin 1/CLDN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0271-Ag | Mouse | Mouse Claudin 1/CLDN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0271-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque Claudin 1/CLDN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0271-Ag | Cat/Feline | Cat/Feline Claudin 1/CLDN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0271-Ag | Dog/Canine | Dog/Canine Claudin 1/CLDN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0271-Ag | Bovines/Cattle | Bovines/Cattle Claudin 1/CLDN1 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0271-Ag | Equine/Horse | Equine/Horse Claudin 1/CLDN1 VLP (virus-like particle) | HEK293 | Products Developing |
