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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined. [provided by RefSeq, Feb 2009]
| Target ID |
GM-MP0211
|
| Target Name |
CD3 Delta/CD3D/CD3d
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
915
|
| Gene ID |
100062931 (Equus caballus), 101083107 (Felis catus), 12500 (Mus musculus), 25710 (Rattus norvegicus) 281053 (Bos taurus), 479419 (Canis lupus familiaris), 699582 (Macaca mulatta), 915 (Homo sapiens)
|
| Target Alternative Names |
CD3 Delta,CD3-DELTA,CD3D,CD3DELTA,CD3d,Cd3d,IMD19,T-cell receptor T3 delta chain,T-cell surface glycoprotein CD3 delta chain,T3D,T3d
|
| Uniprot Accession |
P04235,P19377,Q28072,P04234
|
| Protein Sub-location |
Transmembrane Protein
|
| Disease |
cancer
|
| Disease from KEGG |
Hematopoietic cell lineage, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Chagas disease, Measles, Human T-cell leukemia virus 1 infection, Epstein-Barr virus infection, PD-L1 expression and PD-1 checkpoint pathway in cancer
|
| Gene Ensembl |
ENSECAG00000018190, ENSMUSG00000032094, ENSBTAG00000006452, ENSCAFG00845002450, ENSMMUG00000049268, ENSG00000167286
|
Pre-made viral vector of CD3 Delta/CD3D/CD3d cDNA Clones/ORF Plasmid
CD3 Delta/CD3D/CD3d siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo915 | Pre-made Human CD3D/T3D/IMD19 siRNA oligo Duplex | 915 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25710 | Pre-made Rat Cd3d siRNA oligo Duplex | 25710 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12500 | Pre-made Mouse Cd3d/T3d siRNA oligo Duplex | 12500 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo699582 | Pre-made Cynomolgus/Rhesus macaque CD3D siRNA oligo Duplex | 699582 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101083107 | Pre-made Cat/Feline CD3D siRNA oligo Duplex | 101083107 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479419 | Pre-made Dog/Canine CD3D siRNA oligo Duplex | 479419 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281053 | Pre-made Bovines/Cattle CD3D siRNA oligo Duplex | 281053 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100062931 | Pre-made Equine/Horse CD3D siRNA oligo Duplex | 100062931 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD3 Delta/CD3D/CD3d antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0211-Ab | Human | Anti-Human CD3 Delta/CD3D/CD3d monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0211-Ab | Rat | Anti-Rat CD3 Delta/CD3D/CD3d monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0211-Ab | Mouse | Anti-Mouse CD3 Delta/CD3D/CD3d monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0211-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD3 Delta/CD3D/CD3d monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0211-Ab | Cat/Feline | Anti-Cat/Feline CD3 Delta/CD3D/CD3d monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0211-Ab | Dog/Canine | Anti-Dog/Canine CD3 Delta/CD3D/CD3d monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0211-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD3 Delta/CD3D/CD3d monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0211-Ab | Equine/Horse | Anti-Equine/Horse CD3 Delta/CD3D/CD3d monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CD3 Delta/CD3D/CD3d VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0211-Ag | Human | Human CD3 Delta/CD3D/CD3d VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0211-Ag | Rat | Rat CD3 Delta/CD3D/CD3d VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0211-Ag | Mouse | Mouse CD3 Delta/CD3D/CD3d VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0211-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD3 Delta/CD3D/CD3d VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0211-Ag | Cat/Feline | Cat/Feline CD3 Delta/CD3D/CD3d VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0211-Ag | Dog/Canine | Dog/Canine CD3 Delta/CD3D/CD3d VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0211-Ag | Bovines/Cattle | Bovines/Cattle CD3 Delta/CD3D/CD3d VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0211-Ag | Equine/Horse | Equine/Horse CD3 Delta/CD3D/CD3d VLP (virus-like particle) | HEK293 | Products Developing |