Explore CD247 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Transmembrane Protein.
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-MP0204
|
| Target Name |
CD247
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
919
|
| Gene ID |
100051432 (Equus caballus), 101080604 (Felis catus), 12503 (Mus musculus), 25300 (Rattus norvegicus)
281056 (Bos taurus), 611571 (Canis lupus familiaris), 697814 (Macaca mulatta), 919 (Homo sapiens)
|
| Target Alternative Names |
CD247,Cd247,Cd3,T3z,Cd3h,Cd3z,Tcrk,Tcrz,Cd3-eta,Cd3zeta,Cd3-zeta,4930549J05Rik,A430104F18Rik,TCRzeta,CD3Z,T3Z,CD3H,CD3Q,TCRZ,IMD25,CD3ZETA,CD3-ZETA
|
| Uniprot Accession |
P24161,P20963
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
|
| Disease |
|
| Disease from KEGG |
Natural killer cell mediated cytotoxicity, Th1 and Th2 cell differentiation, Th17 cell differentiation, T cell receptor signaling pathway, Chagas disease, Epstein-Barr virus infection, PD-L1 expression and PD-1 checkpoint pathway in cancer
|
| Gene Ensembl |
ENSECAG00000020158, ENSMUSG00000005763, ENSBTAG00000012700, ENSCAFG00845003466, ENSG00000198821
|
| Target Classification |
|
Pre-made viral vector of CD247 cDNA Clones/ORF Plasmid
CD247 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo919 | Pre-made Human CD247/T3Z/CD3H siRNA oligo Duplex | 919 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25300 | Pre-made Rat Cd247/Cd3z/TCRzeta siRNA oligo Duplex | 25300 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12503 | Pre-made Mouse Cd247/Cd3/T3z siRNA oligo Duplex | 12503 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo697814 | Pre-made Cynomolgus/Rhesus macaque CD247/CD3Z siRNA oligo Duplex | 697814 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080604 | Pre-made Cat/Feline CD247 siRNA oligo Duplex | 101080604 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611571 | Pre-made Dog/Canine CD247 siRNA oligo Duplex | 611571 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo281056 | Pre-made Bovines/Cattle CD247/CD3Z siRNA oligo Duplex | 281056 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051432 | Pre-made Equine/Horse CD247 siRNA oligo Duplex | 100051432 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
CD247 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-MP0204-Ab | Human | Anti-Human CD247 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-rg-MP0204-Ab | Rat | Anti-Rat CD247 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-mg-MP0204-Ab | Mouse | Anti-Mouse CD247 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cynog-MP0204-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque CD247 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-felg-MP0204-Ab | Cat/Feline | Anti-Cat/Feline CD247 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-cang-MP0204-Ab | Dog/Canine | Anti-Dog/Canine CD247 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-bovg-MP0204-Ab | Bovines/Cattle | Anti-Bovines/Cattle CD247 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
| GM-Tg-equg-MP0204-Ab | Equine/Horse | Anti-Equine/Horse CD247 monoclonal antibody | mab | FACS/Biofunctional Antibody | Detail |
CD247 VLP (virus-like particle)
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-MP0204-Ag | Human | Human CD247 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-MP0204-Ag | Rat | Rat CD247 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-MP0204-Ag | Mouse | Mouse CD247 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-MP0204-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque CD247 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-MP0204-Ag | Cat/Feline | Cat/Feline CD247 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-MP0204-Ag | Dog/Canine | Dog/Canine CD247 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-bovg-MP0204-Ag | Bovines/Cattle | Bovines/Cattle CD247 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-equg-MP0204-Ag | Equine/Horse | Equine/Horse CD247 VLP (virus-like particle) | HEK293 | Products Developing |
