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Target
sublocation: Introcelluar Protein.
This gene is located in the candidate region for congenital heart disease (CHD) in Down syndrome (DS). It encodes a basic protein that functions as a receptor that promotes insertion of tail-anchored proteins in the endoplasmic reticulum membrane. This gene is located at a maternally-methylated differentially methylated region (DMR); however, its transcription may be biallelic, not imprinted. Alternative splicing results in different transcript variants. A pseudogene has been defined on chromosome 4. [provided by RefSeq, Apr 2017]
| Target ID |
GM-IP2281
|
| Target Name |
GET1/WRB
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
7485
|
| Gene ID |
100059393 (Equus caballus), 101098734 (Felis catus), 106997239 (Macaca mulatta), 111093447 (Canis lupus familiaris) 288233 (Rattus norvegicus), 509739 (Bos taurus), 71446 (Mus musculus), 7485 (Homo sapiens)
|
| Target Alternative Names |
5530402J05Rik,C030018G21Rik,CHD5,Chd5,Congenital heart disease 5 protein,GET1,Get1,Guided entry of tail-anchored proteins factor 1,Tail-anchored protein insertion receptor WRB,Tryptophan-rich basic protein,WRB,Wrb
|
| Uniprot Accession |
Q6P6S5,Q3SZ26,Q8K0D7,O00258
|
| Protein Sub-location |
Introcelluar Protein
|
| Gene Ensembl |
ENSECAG00000007859, ENSMMUG00000020654, ENSCAFG00845029628, ENSMUSG00000023147, ENSG00000182093
|
Pre-made viral vector of GET1/WRB cDNA Clones/ORF Plasmid
GET1/WRB siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo7485 | Pre-made Human GET1/WRB/CHD5 siRNA oligo Duplex | 7485 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo288233 | Pre-made Rat Get1/Wrb siRNA oligo Duplex | 288233 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo71446 | Pre-made Mouse Get1/Wrb/Chd5 siRNA oligo Duplex | 71446 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo106997239 | Pre-made Cynomolgus/Rhesus macaque GET1/WRB siRNA oligo Duplex | 106997239 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098734 | Pre-made Cat/Feline GET1/WRB siRNA oligo Duplex | 101098734 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo111093447 | Pre-made Dog/Canine GET1 siRNA oligo Duplex | 111093447 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo509739 | Pre-made Bovines/Cattle GET1/WRB siRNA oligo Duplex | 509739 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100059393 | Pre-made Equine/Horse GET1/WRB siRNA oligo Duplex | 100059393 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
GET1/WRB antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP2281-Ab | Human | Anti-Human GET1/WRB monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP2281-Ab | Rat | Anti-Rat GET1/WRB monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP2281-Ab | Mouse | Anti-Mouse GET1/WRB monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP2281-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque GET1/WRB monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP2281-Ab | Cat/Feline | Anti-Cat/Feline GET1/WRB monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP2281-Ab | Dog/Canine | Anti-Dog/Canine GET1/WRB monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP2281-Ab | Bovines/Cattle | Anti-Bovines/Cattle GET1/WRB monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP2281-Ab | Equine/Horse | Anti-Equine/Horse GET1/WRB monoclonal antibody | mab | | Detail |
GET1/WRB recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP2281-Ag | Human | Human GET1/WRB recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP2281-Ag | Rat | Rat GET1/WRB recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP2281-Ag | Mouse | Mouse GET1/WRB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP2281-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque GET1/WRB recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP2281-Ag | Cat/Feline | Cat/Feline GET1/WRB recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP2281-Ag | Dog/Canine | Dog/Canine GET1/WRB recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP2281-Ag | Bovines/Cattle | Bovines/Cattle GET1/WRB recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP2281-Ag | Equine/Horse | Equine/Horse GET1/WRB recombinant protein | Mammalian cell | Detail |