Recombinant multi-species GET1/WRB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GET1/WRB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is located in the candidate region for congenital heart disease (CHD) in Down syndrome (DS). It encodes a basic protein that functions as a receptor that promotes insertion of tail-anchored proteins in the endoplasmic reticulum membrane. This gene is located at a maternally-methylated differentially methylated region (DMR); however, its transcription may be biallelic, not imprinted. Alternative splicing results in different transcript variants. A pseudogene has been defined on chromosome 4. [provided by RefSeq, Apr 2017]
The Alternative Names of target: 5530402J05Rik,C030018G21Rik,CHD5,Chd5,Congenital heart disease 5 protein,GET1,Get1,Guided entry of tail-anchored proteins factor 1,Tail-anchored protein insertion receptor WRB,Tryptophan-rich basic protein,WRB,Wrb

Target products collectionGo to GET1/WRB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP2281-Ag-1/ GM-Tg-hg-IP2281-Ag-2 Human GET1/WRB protein Human
GM-Tg-rg-IP2281-Ag-1/ GM-Tg-rg-IP2281-Ag-2 Rat GET1/WRB protein Rat
GM-Tg-mg-IP2281-Ag-1/ GM-Tg-mg-IP2281-Ag-2 Mouse GET1/WRB protein Mouse
GM-Tg-cynog-IP2281-Ag-1/ GM-Tg-cynog-IP2281-Ag-2 Cynomolgus/Rhesus macaque GET1/WRB protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP2281-Ag-1/ GM-Tg-felg-IP2281-Ag-2 Feline GET1/WRB protein Feline
GM-Tg-cang-IP2281-Ag-1/ GM-Tg-cang-IP2281-Ag-2 Canine GET1/WRB protein Canine
GM-Tg-bovg-IP2281-Ag-1/ GM-Tg-bovg-IP2281-Ag-2 Bovine GET1/WRB protein Bovine
GM-Tg-equg-IP2281-Ag-1/ GM-Tg-equg-IP2281-Ag-2 Equine GET1/WRB protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP2281-Ag-1/ GM-Tg-hg-IP2281-Ag-2; GM-Tg-rg-IP2281-Ag-1/ GM-Tg-rg-IP2281-Ag-2;
GM-Tg-mg-IP2281-Ag-1/ GM-Tg-mg-IP2281-Ag-2; GM-Tg-cynog-IP2281-Ag-1/ GM-Tg-cynog-IP2281-Ag-2;
GM-Tg-felg-IP2281-Ag-1/ GM-Tg-felg-IP2281-Ag-2; GM-Tg-cang-IP2281-Ag-1/ GM-Tg-cang-IP2281-Ag-2;
GM-Tg-bovg-IP2281-Ag-1/ GM-Tg-bovg-IP2281-Ag-2; GM-Tg-equg-IP2281-Ag-1/ GM-Tg-equg-IP2281-Ag-2
Products Name GET1/WRB protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name GET1/WRB
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GET1/WRB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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