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biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP1810
|
| Target Name |
SPI1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
6688
|
| Gene ID |
100051397 (Equus caballus), 101094951 (Felis catus), 20375 (Mus musculus), 366126 (Rattus norvegicus)
507100 (Bos taurus), 611255 (Canis lupus familiaris), 6688 (Homo sapiens), 712010 (Macaca mulatta)
|
| Target Alternative Names |
SPI1,Spi1,SPI1/PU.1,Dis1,PU.1,Dis-1,Sfpi1,Spi-1,Sfpi-1,Tcfpu1,Tfpu.1,Pu.1,OF,AGM10,SFPI1,SPI-1,SPI-A
|
| Uniprot Accession |
P17433,Q6BDS1,P17947
|
| Uniprot Entry Name |
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
|
| Disease |
cancer
|
| Disease from KEGG |
Osteoclast differentiation, Human T-cell leukemia virus 1 infection, Pathways in cancer, Acute myeloid leukemia
|
| Gene Ensembl |
ENSECAG00000024457, ENSMUSG00000002111, ENSBTAG00000021709, ENSG00000066336, ENSMMUG00000015606
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of SPI1 cDNA Clones/ORF Plasmid
SPI1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo6688 | Pre-made Human SPI1/OF/PU.1 siRNA oligo Duplex | 6688 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo366126 | Pre-made Rat Spi1/Pu.1/Sfpi1 siRNA oligo Duplex | 366126 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20375 | Pre-made Mouse Spi1/Dis1/PU.1 siRNA oligo Duplex | 20375 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo712010 | Pre-made Cynomolgus/Rhesus macaque SPI1 siRNA oligo Duplex | 712010 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101094951 | Pre-made Cat/Feline SPI1 siRNA oligo Duplex | 101094951 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo611255 | Pre-made Dog/Canine SPI1 siRNA oligo Duplex | 611255 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo507100 | Pre-made Bovines/Cattle SPI1 siRNA oligo Duplex | 507100 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100051397 | Pre-made Equine/Horse SPI1/SPI1/PU.1 siRNA oligo Duplex | 100051397 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
SPI1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP1810-Ab | Human | Anti-Human SPI1 monoclonal antibody | mab | | Detail |
| GM-Tg-rg-IP1810-Ab | Rat | Anti-Rat SPI1 monoclonal antibody | mab | | Detail |
| GM-Tg-mg-IP1810-Ab | Mouse | Anti-Mouse SPI1 monoclonal antibody | mab | | Detail |
| GM-Tg-cynog-IP1810-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque SPI1 monoclonal antibody | mab | | Detail |
| GM-Tg-felg-IP1810-Ab | Cat/Feline | Anti-Cat/Feline SPI1 monoclonal antibody | mab | | Detail |
| GM-Tg-cang-IP1810-Ab | Dog/Canine | Anti-Dog/Canine SPI1 monoclonal antibody | mab | | Detail |
| GM-Tg-bovg-IP1810-Ab | Bovines/Cattle | Anti-Bovines/Cattle SPI1 monoclonal antibody | mab | | Detail |
| GM-Tg-equg-IP1810-Ab | Equine/Horse | Anti-Equine/Horse SPI1 monoclonal antibody | mab | | Detail |
SPI1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP1810-Ag | Human | Human SPI1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP1810-Ag | Rat | Rat SPI1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP1810-Ag | Mouse | Mouse SPI1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP1810-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque SPI1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP1810-Ag | Cat/Feline | Cat/Feline SPI1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP1810-Ag | Dog/Canine | Dog/Canine SPI1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP1810-Ag | Bovines/Cattle | Bovines/Cattle SPI1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP1810-Ag | Equine/Horse | Equine/Horse SPI1 recombinant protein | Mammalian cell | Detail |
