Recombinant multi-species SPI1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SPI1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: SPI1,Transcription factor PU.1,31 kDa-transforming protein,OF,PU.1,AGM10,SFPI1,SPI-1,SPI-A

Target products collectionGo to SPI1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-IP1810-Ab-1/ GM-Tg-hg-IP1810-Ab-2 Human SPI1 protein Human
GM-Tg-rg-IP1810-Ab-1/ GM-Tg-rg-IP1810-Ab-2 Rat SPI1 protein Rat
GM-Tg-mg-IP1810-Ab-1/ GM-Tg-mg-IP1810-Ab-2 Mouse SPI1 protein Mouse
GM-Tg-cynog-IP1810-Ab-1/ GM-Tg-cynog-IP1810-Ab-2 Cynomolgus/Rhesus macaque SPI1 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-IP1810-Ab-1/ GM-Tg-felg-IP1810-Ab-2 Feline SPI1 protein Feline
GM-Tg-cang-IP1810-Ab-1/ GM-Tg-cang-IP1810-Ab-2 Canine SPI1 protein Canine
GM-Tg-bovg-IP1810-Ab-1/ GM-Tg-bovg-IP1810-Ab-2 Bovine SPI1 protein Bovine
GM-Tg-equg-IP1810-Ab-1/ GM-Tg-equg-IP1810-Ab-2 Equine SPI1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-IP1810-Ab-1/ GM-Tg-hg-IP1810-Ab-2; GM-Tg-rg-IP1810-Ab-1/ GM-Tg-rg-IP1810-Ab-2;
GM-Tg-mg-IP1810-Ab-1/ GM-Tg-mg-IP1810-Ab-2; GM-Tg-cynog-IP1810-Ab-1/ GM-Tg-cynog-IP1810-Ab-2;
GM-Tg-felg-IP1810-Ab-1/ GM-Tg-felg-IP1810-Ab-2; GM-Tg-cang-IP1810-Ab-1/ GM-Tg-cang-IP1810-Ab-2;
GM-Tg-bovg-IP1810-Ab-1/ GM-Tg-bovg-IP1810-Ab-2; GM-Tg-equg-IP1810-Ab-1/ GM-Tg-equg-IP1810-Ab-2
Products Name SPI1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name SPI1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SPI1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.