Explore BAK/BAK1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq, Jul 2008]
| Target ID |
GM-IP0150
|
| Target Name |
BAK/BAK1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
578
|
| Gene ID |
100061755 (Equus caballus), 101093435 (Felis catus), 116502 (Rattus norvegicus), 12018 (Mus musculus)
481744 (Canis lupus familiaris), 514090 (Bos taurus), 578 (Homo sapiens), 706534 (Macaca mulatta)
|
| Target Alternative Names |
Apoptosis regulator BAK,BAK,BAK-LIKE,BAK1,BCL2L7,Bak,Bak1,Bcl-2 homologous antagonist/killer,Bcl-2-like protein 7 (Bcl2-L-7),CDN1,N-BAK1,N-Bak
|
| Uniprot Accession |
O08734,Q16611
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
Protein processing in endoplasmic reticulum, Apoptosis, Apoptosis - multiple species, Pathogenic Escherichia coli infection, Hepatitis C, Measles, Human cytomegalovirus infection, Influenza A, Human papillomavirus infection, Kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection, Pathways in cancer, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Glioma, Thyroid cancer, Basal cell carcinoma, Melanoma, Chronic myeloid leukemia, Small cell lung cancer, Non-small cell lung cancer, Breast cancer, Hepatocellular carcinoma, Gastric cancer
|
| Gene Ensembl |
ENSECAG00000023902, ENSMUSG00000057789, ENSCAFG00845023547, ENSG00000030110, ENSMMUG00000063304
|
| Target Classification |
Tumor-associated antigen (TAA)
|
Pre-made viral vector of BAK/BAK1 cDNA Clones/ORF Plasmid
BAK/BAK1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo578 | Pre-made Human BAK1/BAK/CDN1 siRNA oligo Duplex | 578 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo116502 | Pre-made Rat Bak1/Bak siRNA oligo Duplex | 116502 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo12018 | Pre-made Mouse Bak1/Bak/N-Bak siRNA oligo Duplex | 12018 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo706534 | Pre-made Cynomolgus/Rhesus macaque BAK1 siRNA oligo Duplex | 706534 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101093435 | Pre-made Cat/Feline BAK1 siRNA oligo Duplex | 101093435 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo481744 | Pre-made Dog/Canine BAK1 siRNA oligo Duplex | 481744 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo514090 | Pre-made Bovines/Cattle BAK1 siRNA oligo Duplex | 514090 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100061755 | Pre-made Equine/Horse BAK1 siRNA oligo Duplex | 100061755 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
BAK/BAK1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0150-Ab | Human | Anti-Human BAK/BAK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0150-Ab | Rat | Anti-Rat BAK/BAK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0150-Ab | Mouse | Anti-Mouse BAK/BAK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0150-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque BAK/BAK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0150-Ab | Cat/Feline | Anti-Cat/Feline BAK/BAK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0150-Ab | Dog/Canine | Anti-Dog/Canine BAK/BAK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0150-Ab | Bovines/Cattle | Anti-Bovines/Cattle BAK/BAK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0150-Ab | Equine/Horse | Anti-Equine/Horse BAK/BAK1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
BAK/BAK1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0150-Ag | Human | Human BAK/BAK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0150-Ag | Rat | Rat BAK/BAK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0150-Ag | Mouse | Mouse BAK/BAK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0150-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque BAK/BAK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0150-Ag | Cat/Feline | Cat/Feline BAK/BAK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0150-Ag | Dog/Canine | Dog/Canine BAK/BAK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0150-Ag | Bovines/Cattle | Bovines/Cattle BAK/BAK1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0150-Ag | Equine/Horse | Equine/Horse BAK/BAK1 recombinant protein | Mammalian cell | Detail |
