Explore MCL1 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Introcelluar Protein.
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing. [provided by RefSeq, Oct 2010]
| Target ID |
GM-IP0049
|
| Target Name |
MCL1
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
4170
|
| Gene ID |
100054765 (Equus caballus), 17210 (Mus musculus), 403537 (Canis lupus familiaris), 4170 (Homo sapiens)
493970 (Felis catus), 60430 (Rattus norvegicus), 707539 (Macaca mulatta), 788087 (Bos taurus)
|
| Target Alternative Names |
BCL2L3,Bcl-2-like protein 3 (Bcl2-L-3),Bcl-2-related protein EAT/mcl1,EAT,Gm52627,Induced myeloid leukemia cell differentiation protein Mcl-1,MCL1,MCL1-ES,MCL1L,MCL1S,Mcl-1,Mcl1,TM,bcl2-L-3,mcl-1,mcl1/EAT
|
| Uniprot Accession |
P97287,Q8HYS5,Q07820,Q7YRZ9,Q9Z1P3
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
cancer
|
| Disease from KEGG |
PI3K-Akt signaling pathway, Apoptosis, JAK-STAT signaling pathway
|
| Gene Ensembl |
ENSECAG00000018823, ENSMUSG00000038612, ENSCAFG00845018496, ENSG00000143384, ENSMMUG00000053525, ENSBTAG00000015154
|
| Target Classification |
Pathway, Tumor-associated antigen (TAA)
|
Pre-made viral vector of MCL1 cDNA Clones/ORF Plasmid
MCL1 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo4170 | Pre-made Human MCL1/TM/EAT siRNA oligo Duplex | 4170 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo60430 | Pre-made Rat Mcl1 siRNA oligo Duplex | 60430 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo17210 | Pre-made Mouse Mcl1/Mcl-1/Gm52627 siRNA oligo Duplex | 17210 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo707539 | Pre-made Cynomolgus/Rhesus macaque MCL1 siRNA oligo Duplex | 707539 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493970 | Pre-made Cat/Feline MCL1/mcl-1 siRNA oligo Duplex | 493970 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403537 | Pre-made Dog/Canine MCL1 siRNA oligo Duplex | 403537 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo788087 | Pre-made Bovines/Cattle MCL1 siRNA oligo Duplex | 788087 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100054765 | Pre-made Equine/Horse MCL1 siRNA oligo Duplex | 100054765 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
MCL1 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IP0049-Ab | Human | Anti-Human MCL1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-IP0049-Ab | Rat | Anti-Rat MCL1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-IP0049-Ab | Mouse | Anti-Mouse MCL1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-IP0049-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque MCL1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-IP0049-Ab | Cat/Feline | Anti-Cat/Feline MCL1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-IP0049-Ab | Dog/Canine | Anti-Dog/Canine MCL1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-IP0049-Ab | Bovines/Cattle | Anti-Bovines/Cattle MCL1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-IP0049-Ab | Equine/Horse | Anti-Equine/Horse MCL1 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
MCL1 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IP0049-Ag | Human | Human MCL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-IP0049-Ag | Rat | Rat MCL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-IP0049-Ag | Mouse | Mouse MCL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-IP0049-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque MCL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-IP0049-Ag | Cat/Feline | Cat/Feline MCL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-IP0049-Ag | Dog/Canine | Dog/Canine MCL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-IP0049-Ag | Bovines/Cattle | Bovines/Cattle MCL1 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-IP0049-Ag | Equine/Horse | Equine/Horse MCL1 recombinant protein | Mammalian cell | Detail |
