Human MCL1/bcl2-L-3/BCL2L3 ORF/cDNA clone-Lentivirus particle (NM_021960)

Cat. No.: vGMLP005087

Pre-made Human MCL1/bcl2-L-3/BCL2L3 Lentiviral expression plasmid for MCL1 lentivirus packaging, MCL1 lentivirus production, overexpression stable cell line development, cell transient transfection and gene delivery targeting T/B/NK cells, macrophages, cardiomyocytes, hepatocytes, and neurons.

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Product information

Catalog No. Product Name lentivirus Grade lentivirus quantity
vGMLP005087 Human MCL1 Lentivirus particle Pilot Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
Research Grade 1.0E+8TU
5.0E+8TU
1.0E+9TU
GMP-like Grade inquiry
GMP Grade inquiry


Product Description

Catalog ID vGMLP005087
Gene Name MCL1
Accession Number NM_021960
Gene ID 4170
Species Human
Product Type Lentivirus particle (overexpression)
Insert Length 1053 bp
Gene Alias bcl2-L-3,BCL2L3,EAT,Mcl-1,MCL1-ES,mcl1/EAT,MCL1L,MCL1S,TM
Fluorescent Reporter ZsGreen
Mammalian Cell Selection Puromyocin
Fusion Tag 3xflag (C-Terminal)
Promoter CMV
Resistance Amplicin
ORF Nucleotide Sequence ATGTTTGGCCTCAAAAGAAACGCGGTAATCGGACTCAACCTCTACTGTGGGGGGGCCGGCTTGGGGGCCGGCAGCGGCGGCGCCACCCGCCCGGGAGGGCGACTTTTGGCTACGGAGAAGGAGGCCTCGGCCCGGCGAGAGATAGGGGGAGGGGAGGCCGGCGCGGTGATTGGCGGAAGCGCCGGCGCAAGCCCCCCGTCCACCCTCACGCCAGACTCCCGGAGGGTCGCGCGGCCGCCGCCCATTGGCGCCGAGGTCCCCGACGTCACCGCGACCCCCGCGAGGCTGCTTTTCTTCGCGCCCACCCGCCGCGCGGCGCCGCTTGAGGAGATGGAAGCCCCGGCCGCTGACGCCATCATGTCGCCCGAAGAGGAGCTGGACGGGTACGAGCCGGAGCCTCTCGGGAAGCGGCCGGCTGTCCTGCCGCTGCTGGAGTTGGTCGGGGAATCTGGTAATAACACCAGTACGGACGGGTCACTACCCTCGACGCCGCCGCCAGCAGAGGAGGAGGAGGACGAGTTGTACCGGCAGTCGCTGGAGATTATCTCTCGGTACCTTCGGGAGCAGGCCACCGGCGCCAAGGACACAAAGCCAATGGGCAGGTCTGGGGCCACCAGCAGGAAGGCGCTGGAGACCTTACGACGGGTTGGGGATGGCGTGCAGCGCAACCACGAGACGGCCTTCCAAGGCATGCTTCGGAAACTGGACATCAAAAACGAAGACGATGTGAAATCGTTGTCTCGAGTGATGATCCATGTTTTCAGCGACGGCGTAACAAACTGGGGCAGGATTGTGACTCTCATTTCTTTTGGTGCCTTTGTGGCTAAACACTTGAAGACCATAAACCAAGAAAGCTGCATCGAACCATTAGCAGAAAGTATCACAGACGTTCTCGTAAGGACAAAACGGGACTGGCTAGTTAAACAAAGAGGCTGGGATGGGTTTGTGGAGTTCTTCCATGTAGAGGACCTAGAAGGTGGCATCAGGAATGTGCTGCTGGCTTTTGCAGGTGTTGCTGGAGTAGGAGCTGGTTTGGCATATCTAATAAGATAG
ORF Protein Sequence MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGSAGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIMSPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR

Reference




    Data / case study


    Click to get more Data / Case study about the product.



    Associated products


    Category Cat No. Products Name
    Target Antibody GM-Tg-g-IP0049-Ab Anti-MCL1 monoclonal antibody
    Target Antigen GM-Tg-g-IP0049-Ag MCL1 protein
    ORF Viral Vector pGMLP005087 Human MCL1 Lentivirus plasmid
    ORF Viral Vector vGMLP005087 Human MCL1 Lentivirus particle


    Target information

    Target ID GM-IP0049
    Target Name MCL1
    Gene Group Identifier
    （Target Gene ID in Homo species)         		4170
    Gene ID 100054765 (Equus caballus), 17210 (Mus musculus), 403537 (Canis lupus familiaris), 4170 (Homo sapiens)
    493970 (Felis catus), 60430 (Rattus norvegicus), 707539 (Macaca mulatta), 788087 (Bos taurus)
    Gene Symbols & Synonyms MCL1,Mcl1,Mcl-1,Gm52627,TM,EAT,MCL1L,MCL1S,BCL2L3,MCL1-ES,bcl2-L-3,mcl1/EAT,mcl-1
    Target Alternative Names BCL2L3,Bcl-2-like protein 3 (Bcl2-L-3),Bcl-2-related protein EAT/mcl1,EAT,Gm52627,Induced myeloid leukemia cell differentiation protein Mcl-1,MCL1,MCL1-ES,MCL1L,MCL1S,Mcl-1,Mcl1,TM,bcl2-L-3,mcl-1,mcl1/EAT
    Uniprot Accession P97287,Q07820,Q7YRZ9,Q8HYS5,Q9Z1P3
    Additional SwissProt Accessions: P97287,Q8HYS5,Q07820,Q7YRZ9,Q9Z1P3
    Uniprot Entry Name
    Protein Sub-location Introcelluar Protein
    Category Therapeutics Target
    Disease cancer
    Disease from KEGG PI3K-Akt signaling pathway, Apoptosis, JAK-STAT signaling pathway
    Gene Ensembl ENSECAG00000018823, ENSMUSG00000038612, ENSCAFG00845018496, ENSG00000143384, ENSMMUG00000053525, ENSBTAG00000015154
    Target Classification Pathway, Tumor-associated antigen (TAA)


    About GMVC

    GDU

    GMVC (GM Vector Core) is GeneMedi’s unique platform for QbD Viral vectors Processes development and manufacturing. In GMVC, our core expertise lies in the tailored production of viral vectors, including adeno-associated virus (AAV), lentivirus, and adenovirus. Our state-of-the-art facilities are equipped for scalable manufacturing, ensuring high-quality viral vector production to meet both research and therapeutic needs. Our expert team specializes in process development, leveraging innovative technology and extensive industry knowledge to provide clients with tailored solutions that exceed expectations. GMVC will be the ideal partner for scientists and healthcare professionals seeking reliable and efficient viral vector production services.