Bcl-XL/Bcl-xL/BCL2L1/BCL-xL Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore Bcl-XL/Bcl-xL/BCL2L1/BCL-xL gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator. [provided by RefSeq, Dec 2015]

Pre-made viral vector of Bcl-XL/Bcl-xL/BCL2L1/BCL-xL cDNA Clones/ORF Plasmid

Bcl-XL/Bcl-xL/BCL2L1/BCL-xL siRNA/miRNA/oligo for RNA interfence (RNAi)

Bcl-XL/Bcl-xL/BCL2L1/BCL-xL antibody/GMab

Bcl-XL/Bcl-xL/BCL2L1/BCL-xL recombinant protein