Explore HVEM/TNFRSF14/CD270 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
premier destination for multi-species gene research solutions
Target
sublocation: Transmembrane Protein.
This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
| Target ID |
GM-IO063
|
| Target Name |
HVEM/TNFRSF14/CD270
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
8764
|
| Gene ID |
101089877 (Felis catus), 230979 (Mus musculus), 366518 (Rattus norvegicus), 479580 (Canis lupus familiaris)
695042 (Macaca mulatta), 8764 (Homo sapiens)
|
| Target Alternative Names |
ATAR,Atar,CD270,HVEA,HVEM,Herpes virus entry mediator A (Herpesvirus entry mediator A,HveA,HveA),Hvem,LIGHTR,TNFRSF14,TR2,Tnfrs14,Tnfrsf14,Tumor necrosis factor receptor superfamily member 14,Tumor necrosis factor receptor-like 2 (TR2)
|
| Uniprot Accession |
Q80WM9,Q92956
|
| Protein Sub-location |
Transmembrane Protein
|
| Category |
Therapeutics Target, Immuno-oncology Target, Cytokine Target
|
| Disease |
cancer
|
| Disease from KEGG |
Cytokine-cytokine receptor interaction, Viral protein interaction with cytokine and cytokine receptor
|
| Gene Ensembl |
ENSMUSG00000042333, ENSMMUG00000016329, ENSG00000157873
|
| Target Classification |
Checkpoint-Immuno Oncology
|
Pre-made viral vector of HVEM/TNFRSF14/CD270 cDNA Clones/ORF Plasmid
HVEM/TNFRSF14/CD270 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo8764 | Pre-made Human TNFRSF14/TR2/ATAR siRNA oligo Duplex | 8764 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo366518 | Pre-made Rat Tnfrsf14 siRNA oligo Duplex | 366518 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo230979 | Pre-made Mouse Tnfrsf14/TR2/Atar siRNA oligo Duplex | 230979 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo695042 | Pre-made Cynomolgus/Rhesus macaque TNFRSF14 siRNA oligo Duplex | 695042 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089877 | Pre-made Cat/Feline TNFRSF14 siRNA oligo Duplex | 101089877 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479580 | Pre-made Dog/Canine TNFRSF14/HVEM siRNA oligo Duplex | 479580 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
HVEM/TNFRSF14/CD270 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-IO063-Ab | Human | Anti-Human HVEM/TNFRSF14/CD270 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-rg-IO063-Ab | Rat | Anti-Rat HVEM/TNFRSF14/CD270 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-mg-IO063-Ab | Mouse | Anti-Mouse HVEM/TNFRSF14/CD270 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cynog-IO063-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HVEM/TNFRSF14/CD270 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-felg-IO063-Ab | Cat/Feline | Anti-Cat/Feline HVEM/TNFRSF14/CD270 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
| GM-Tg-cang-IO063-Ab | Dog/Canine | Anti-Dog/Canine HVEM/TNFRSF14/CD270 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Cytokine antibody | Detail |
HVEM/TNFRSF14/CD270 VLP (virus-like particle)/protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-IO063-Ag | Human | Human HVEM/TNFRSF14/CD270 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-rg-IO063-Ag | Rat | Rat HVEM/TNFRSF14/CD270 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-mg-IO063-Ag | Mouse | Mouse HVEM/TNFRSF14/CD270 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cynog-IO063-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HVEM/TNFRSF14/CD270 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-felg-IO063-Ag | Cat/Feline | Cat/Feline HVEM/TNFRSF14/CD270 VLP (virus-like particle) | HEK293 | Products Developing |
| GM-Tg-cang-IO063-Ag | Dog/Canine | Dog/Canine HVEM/TNFRSF14/CD270 VLP (virus-like particle) | HEK293 | Products Developing |
