Recombinant multi-species PLCG2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PLCG2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. [provided by RefSeq, Mar 2014]
The Alternative Names of target: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2,APLAID,FCAS3,PLC-IV,PLC-gamma-2,PLCG2,PLCgamma2,Phosphoinositide phospholipase C-gamma-2,Phospholipase C-IV (PLC-IV),Phospholipase C-gamma-2 (PLC-gamma-2),Plcg-2,Plcg2

Target products collectionGo to PLCG2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-TA116-Ag-1/ GM-Tg-hg-TA116-Ag-2 Human PLCG2 protein Human
GM-Tg-rg-TA116-Ag-1/ GM-Tg-rg-TA116-Ag-2 Rat PLCG2 protein Rat
GM-Tg-mg-TA116-Ag-1/ GM-Tg-mg-TA116-Ag-2 Mouse PLCG2 protein Mouse
GM-Tg-cynog-TA116-Ag-1/ GM-Tg-cynog-TA116-Ag-2 Cynomolgus/Rhesus macaque PLCG2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-TA116-Ag-1/ GM-Tg-felg-TA116-Ag-2 Feline PLCG2 protein Feline
GM-Tg-cang-TA116-Ag-1/ GM-Tg-cang-TA116-Ag-2 Canine PLCG2 protein Canine
GM-Tg-bovg-TA116-Ag-1/ GM-Tg-bovg-TA116-Ag-2 Bovine PLCG2 protein Bovine
GM-Tg-equg-TA116-Ag-1/ GM-Tg-equg-TA116-Ag-2 Equine PLCG2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-TA116-Ag-1/ GM-Tg-hg-TA116-Ag-2; GM-Tg-rg-TA116-Ag-1/ GM-Tg-rg-TA116-Ag-2;
GM-Tg-mg-TA116-Ag-1/ GM-Tg-mg-TA116-Ag-2; GM-Tg-cynog-TA116-Ag-1/ GM-Tg-cynog-TA116-Ag-2;
GM-Tg-felg-TA116-Ag-1/ GM-Tg-felg-TA116-Ag-2; GM-Tg-cang-TA116-Ag-1/ GM-Tg-cang-TA116-Ag-2;
GM-Tg-bovg-TA116-Ag-1/ GM-Tg-bovg-TA116-Ag-2; GM-Tg-equg-TA116-Ag-1/ GM-Tg-equg-TA116-Ag-2
Products Name PLCG2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PLCG2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PLCG2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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