Recombinant multi-species AMPK Beta 1/PRKAB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AMPK Beta 1/PRKAB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 1300015D22Rik,5'-AMP-activated protein kinase subunit beta-1,AMPK,AMPK Beta 1,AMPK subunit beta-1,AMPKb,E430008F22,HAMPKb,PRKAB1,Prkab1

Target products collectionGo to AMPK Beta 1/PRKAB1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-TA082-Ag-1/ GM-Tg-hg-TA082-Ag-2 Human AMPK Beta 1/PRKAB1 protein Human
GM-Tg-rg-TA082-Ag-1/ GM-Tg-rg-TA082-Ag-2 Rat AMPK Beta 1/PRKAB1 protein Rat
GM-Tg-mg-TA082-Ag-1/ GM-Tg-mg-TA082-Ag-2 Mouse AMPK Beta 1/PRKAB1 protein Mouse
GM-Tg-cynog-TA082-Ag-1/ GM-Tg-cynog-TA082-Ag-2 Cynomolgus/Rhesus macaque AMPK Beta 1/PRKAB1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-TA082-Ag-1/ GM-Tg-felg-TA082-Ag-2 Feline AMPK Beta 1/PRKAB1 protein Feline
GM-Tg-cang-TA082-Ag-1/ GM-Tg-cang-TA082-Ag-2 Canine AMPK Beta 1/PRKAB1 protein Canine
GM-Tg-bovg-TA082-Ag-1/ GM-Tg-bovg-TA082-Ag-2 Bovine AMPK Beta 1/PRKAB1 protein Bovine
GM-Tg-equg-TA082-Ag-1/ GM-Tg-equg-TA082-Ag-2 Equine AMPK Beta 1/PRKAB1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-TA082-Ag-1/ GM-Tg-hg-TA082-Ag-2; GM-Tg-rg-TA082-Ag-1/ GM-Tg-rg-TA082-Ag-2;
GM-Tg-mg-TA082-Ag-1/ GM-Tg-mg-TA082-Ag-2; GM-Tg-cynog-TA082-Ag-1/ GM-Tg-cynog-TA082-Ag-2;
GM-Tg-felg-TA082-Ag-1/ GM-Tg-felg-TA082-Ag-2; GM-Tg-cang-TA082-Ag-1/ GM-Tg-cang-TA082-Ag-2;
GM-Tg-bovg-TA082-Ag-1/ GM-Tg-bovg-TA082-Ag-2; GM-Tg-equg-TA082-Ag-1/ GM-Tg-equg-TA082-Ag-2
Products Name AMPK Beta 1/PRKAB1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name AMPK Beta 1/PRKAB1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AMPK Beta 1/PRKAB1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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