AMPK Beta 1/PRKAB1 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore AMPK Beta 1/PRKAB1 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008]

Target ID GM-TA082
Target Name AMPK Beta 1/PRKAB1
Gene Group ldentifer
(Target Gene ID in Homo species)
5564
Gene ID 100034094 (Equus caballus), 101094051 (Felis catus), 19079 (Mus musculus), 486295 (Canis lupus familiaris)
534107 (Bos taurus), 5564 (Homo sapiens), 695737 (Macaca mulatta), 83803 (Rattus norvegicus)
Target Alternative Names 1300015D22Rik,5'-AMP-activated protein kinase subunit beta-1,AMPK,AMPK Beta 1,AMPK subunit beta-1,AMPKb,E430008F22,HAMPKb,PRKAB1,Prkab1
Uniprot Accession Q9R078,Q5BIS9,Q9Y478,P80386
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Disease from KEGG FoxO signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Tight junction, Adipocytokine signaling pathway, Oxytocin signaling pathway, Insulin resistance, Alcoholic liver disease, Hypertrophic cardiomyopathy
Gene Ensembl ENSECAG00000011947, ENSMUSG00000029513, ENSCAFG00845028956, ENSBTAG00000005940, ENSG00000111725, ENSMMUG00000019860


Pre-made viral vector of AMPK Beta 1/PRKAB1 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP001018Human PRKAB1/AMPK/HAMPKb Lentivirus plasmidNM_0062535564HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLP005189Human PRKAB1/AMPK/HAMPKb Lentivirus plasmidNM_006253.45564HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMLP005644Human PRKAB1/AMPK/HAMPKb Lentivirus plasmidNM_006253.45564HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
pGMPC001334Human PRKAB1/AMPK/HAMPKb Mammalian (Non-Viral Vector) plasmidNM_006253.55564HumanMammalian (Non-Viral Vector) plasmidEGFP3xflag (C-Terminal)EF1Detail
vGMLP001018Human PRKAB1/AMPK/HAMPKb Lentivirus particleNM_0062535564HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLP005189Human PRKAB1/AMPK/HAMPKb Lentivirus particleNM_006253.45564HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
vGMLP005644Human PRKAB1/AMPK/HAMPKb Lentivirus particleNM_006253.45564HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail
pGMLPm000618Mouse Prkab1/1300015D22Rik/AU021155 Lentivirus plasmidNM_03186919079MouseLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLPm000618Mouse Prkab1/1300015D22Rik/AU021155 Lentivirus particleNM_03186919079MouseLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


AMPK Beta 1/PRKAB1 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo5564Pre-made Human PRKAB1/AMPK/HAMPKb siRNA oligo Duplex5564HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo83803Pre-made Rat Prkab1 siRNA oligo Duplex83803RatIn-vitro grade; in-vivo gradeDetail
pGMoligo19079Pre-made Mouse Prkab1/E430008F22/1300015D22Rik siRNA oligo Duplex19079MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo695737Pre-made Cynomolgus/Rhesus macaque PRKAB1 siRNA oligo Duplex695737Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101094051Pre-made Cat/Feline PRKAB1 siRNA oligo Duplex101094051Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo486295Pre-made Dog/Canine PRKAB1 siRNA oligo Duplex486295Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo534107Pre-made Bovines/Cattle PRKAB1 siRNA oligo Duplex534107Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100034094Pre-made Equine/Horse PRKAB1 siRNA oligo Duplex100034094Equine/HorseIn-vitro grade; in-vivo gradeDetail


AMPK Beta 1/PRKAB1 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-TA082-AbHumanAnti-Human AMPK Beta 1/PRKAB1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-TA082-AbRatAnti-Rat AMPK Beta 1/PRKAB1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-TA082-AbMouseAnti-Mouse AMPK Beta 1/PRKAB1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-TA082-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque AMPK Beta 1/PRKAB1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-TA082-AbCat/FelineAnti-Cat/Feline AMPK Beta 1/PRKAB1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-TA082-AbDog/CanineAnti-Dog/Canine AMPK Beta 1/PRKAB1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-TA082-AbBovines/CattleAnti-Bovines/Cattle AMPK Beta 1/PRKAB1 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-TA082-AbEquine/HorseAnti-Equine/Horse AMPK Beta 1/PRKAB1 monoclonal antibodymabTherapeutics Target antibodyDetail


AMPK Beta 1/PRKAB1 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-TA082-AgHumanHuman AMPK Beta 1/PRKAB1 recombinant proteinMammalian cellDetail
GM-Tg-rg-TA082-AgRatRat AMPK Beta 1/PRKAB1 recombinant proteinMammalian cellDetail
GM-Tg-mg-TA082-AgMouseMouse AMPK Beta 1/PRKAB1 recombinant proteinMammalian cellDetail
GM-Tg-cynog-TA082-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque AMPK Beta 1/PRKAB1 recombinant proteinMammalian cellDetail
GM-Tg-felg-TA082-AgCat/FelineCat/Feline AMPK Beta 1/PRKAB1 recombinant proteinMammalian cellDetail
GM-Tg-cang-TA082-AgDog/CanineDog/Canine AMPK Beta 1/PRKAB1 recombinant proteinMammalian cellDetail
GM-Tg-bovg-TA082-AgBovines/CattleBovines/Cattle AMPK Beta 1/PRKAB1 recombinant proteinMammalian cellDetail
GM-Tg-equg-TA082-AgEquine/HorseEquine/Horse AMPK Beta 1/PRKAB1 recombinant proteinMammalian cellDetail