Recombinant multi-species Arginase-1/ARG1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Arginase-1/ARG1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
The Alternative Names of target: AI,ARG1,Arg-1,Arg1,Arginase-1,Liver-type arginase,PGIF,Type I arginase

Target products collectionGo to Arginase-1/ARG1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-TA042-Ag-1/ GM-Tg-hg-TA042-Ag-2 Human Arginase-1/ARG1 protein Human
GM-Tg-rg-TA042-Ag-1/ GM-Tg-rg-TA042-Ag-2 Rat Arginase-1/ARG1 protein Rat
GM-Tg-mg-TA042-Ag-1/ GM-Tg-mg-TA042-Ag-2 Mouse Arginase-1/ARG1 protein Mouse
GM-Tg-cynog-TA042-Ag-1/ GM-Tg-cynog-TA042-Ag-2 Cynomolgus/Rhesus macaque Arginase-1/ARG1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-TA042-Ag-1/ GM-Tg-felg-TA042-Ag-2 Feline Arginase-1/ARG1 protein Feline
GM-Tg-cang-TA042-Ag-1/ GM-Tg-cang-TA042-Ag-2 Canine Arginase-1/ARG1 protein Canine
GM-Tg-bovg-TA042-Ag-1/ GM-Tg-bovg-TA042-Ag-2 Bovine Arginase-1/ARG1 protein Bovine
GM-Tg-equg-TA042-Ag-1/ GM-Tg-equg-TA042-Ag-2 Equine Arginase-1/ARG1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-TA042-Ag-1/ GM-Tg-hg-TA042-Ag-2; GM-Tg-rg-TA042-Ag-1/ GM-Tg-rg-TA042-Ag-2;
GM-Tg-mg-TA042-Ag-1/ GM-Tg-mg-TA042-Ag-2; GM-Tg-cynog-TA042-Ag-1/ GM-Tg-cynog-TA042-Ag-2;
GM-Tg-felg-TA042-Ag-1/ GM-Tg-felg-TA042-Ag-2; GM-Tg-cang-TA042-Ag-1/ GM-Tg-cang-TA042-Ag-2;
GM-Tg-bovg-TA042-Ag-1/ GM-Tg-bovg-TA042-Ag-2; GM-Tg-equg-TA042-Ag-1/ GM-Tg-equg-TA042-Ag-2
Products Name Arginase-1/ARG1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Arginase-1/ARG1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Arginase-1/ARG1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.