Recombinant multi-species KGA/GLS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KGA/GLS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
The Alternative Names of target: 6330442B14,AAD20,B230365M23Rik,CASGID,DEE71,EIEE71,GAC,GAM,GDPAG,GLS,GLS1,Gls,Glut,Glutaminase kidney isoform,K-glutaminase,KGA,L-glutamine amidohydrolase,RATGLUT,mitochondrial
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-TA039-Ag-1/ GM-Tg-hg-TA039-Ag-2 | Human KGA/GLS protein | Human |
| GM-Tg-rg-TA039-Ag-1/ GM-Tg-rg-TA039-Ag-2 | Rat KGA/GLS protein | Rat |
| GM-Tg-mg-TA039-Ag-1/ GM-Tg-mg-TA039-Ag-2 | Mouse KGA/GLS protein | Mouse |
| GM-Tg-cynog-TA039-Ag-1/ GM-Tg-cynog-TA039-Ag-2 | Cynomolgus/Rhesus macaque KGA/GLS protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-TA039-Ag-1/ GM-Tg-felg-TA039-Ag-2 | Feline KGA/GLS protein | Feline |
| GM-Tg-cang-TA039-Ag-1/ GM-Tg-cang-TA039-Ag-2 | Canine KGA/GLS protein | Canine |
| GM-Tg-bovg-TA039-Ag-1/ GM-Tg-bovg-TA039-Ag-2 | Bovine KGA/GLS protein | Bovine |
| GM-Tg-equg-TA039-Ag-1/ GM-Tg-equg-TA039-Ag-2 | Equine KGA/GLS protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-TA039-Ag-1/ GM-Tg-hg-TA039-Ag-2;
GM-Tg-rg-TA039-Ag-1/ GM-Tg-rg-TA039-Ag-2;
GM-Tg-mg-TA039-Ag-1/ GM-Tg-mg-TA039-Ag-2; GM-Tg-cynog-TA039-Ag-1/ GM-Tg-cynog-TA039-Ag-2; GM-Tg-felg-TA039-Ag-1/ GM-Tg-felg-TA039-Ag-2; GM-Tg-cang-TA039-Ag-1/ GM-Tg-cang-TA039-Ag-2; GM-Tg-bovg-TA039-Ag-1/ GM-Tg-bovg-TA039-Ag-2; GM-Tg-equg-TA039-Ag-1/ GM-Tg-equg-TA039-Ag-2 |
| Products Name | KGA/GLS protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | KGA/GLS |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine KGA/GLS protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.