Explore KGA/GLS gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]
| Target ID |
GM-TA039
|
| Target Name |
KGA/GLS
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
2744
|
| Gene ID |
100069617 (Equus caballus), 101080395 (Felis catus), 14660 (Mus musculus), 24398 (Rattus norvegicus)
2744 (Homo sapiens), 488448 (Canis lupus familiaris), 525335 (Bos taurus), 693520 (Macaca mulatta)
|
| Target Alternative Names |
6330442B14,AAD20,B230365M23Rik,CASGID,DEE71,EIEE71,GAC,GAM,GDPAG,GLS,GLS1,Gls,Glut,Glutaminase kidney isoform,K-glutaminase,KGA,L-glutamine amidohydrolase,RATGLUT,mitochondrial
|
| Uniprot Accession |
D3Z7P3,P13264,O94925
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, Glutamatergic synapse, GABAergic synapse, Central carbon metabolism in cancer
|
| Gene Ensembl |
ENSECAG00000010549, ENSMUSG00000026103, ENSG00000115419, ENSCAFG00845025512, ENSBTAG00000007863, ENSMMUG00000005612
|
Pre-made viral vector of KGA/GLS cDNA Clones/ORF Plasmid
KGA/GLS siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo2744 | Pre-made Human GLS/GAC/GAM siRNA oligo Duplex | 2744 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24398 | Pre-made Rat Gls/Glut/RATGLUT siRNA oligo Duplex | 24398 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo14660 | Pre-made Mouse Gls/6330442B14/B230365M23Rik siRNA oligo Duplex | 14660 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo693520 | Pre-made Cynomolgus/Rhesus macaque GLS siRNA oligo Duplex | 693520 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101080395 | Pre-made Cat/Feline GLS siRNA oligo Duplex | 101080395 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo488448 | Pre-made Dog/Canine GLS siRNA oligo Duplex | 488448 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo525335 | Pre-made Bovines/Cattle GLS siRNA oligo Duplex | 525335 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100069617 | Pre-made Equine/Horse GLS siRNA oligo Duplex | 100069617 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
KGA/GLS antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA039-Ab | Human | Anti-Human KGA/GLS monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA039-Ab | Rat | Anti-Rat KGA/GLS monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA039-Ab | Mouse | Anti-Mouse KGA/GLS monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA039-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque KGA/GLS monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA039-Ab | Cat/Feline | Anti-Cat/Feline KGA/GLS monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA039-Ab | Dog/Canine | Anti-Dog/Canine KGA/GLS monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA039-Ab | Bovines/Cattle | Anti-Bovines/Cattle KGA/GLS monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA039-Ab | Equine/Horse | Anti-Equine/Horse KGA/GLS monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
KGA/GLS recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA039-Ag | Human | Human KGA/GLS recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-TA039-Ag | Rat | Rat KGA/GLS recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-TA039-Ag | Mouse | Mouse KGA/GLS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-TA039-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque KGA/GLS recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-TA039-Ag | Cat/Feline | Cat/Feline KGA/GLS recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-TA039-Ag | Dog/Canine | Dog/Canine KGA/GLS recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-TA039-Ag | Bovines/Cattle | Bovines/Cattle KGA/GLS recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-TA039-Ag | Equine/Horse | Equine/Horse KGA/GLS recombinant protein | Mammalian cell | Detail |
