Recombinant multi-species HSP70/HSPA1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HSP70/HSPA1A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]
The Alternative Names of target: HEL-S-103,HSP70,HSP70-1,HSP70-1A,HSP70-2,HSP70.1,HSP70.1),HSP70.2,HSP70I,HSP72,HSPA1,HSPA1A,HSPA1B,Heat shock 70 kDa protein 1 (HSP70-1,Heat shock 70 kDa protein 1A,Heat shock protein family A member 1A,Hsp70,Hsp70-3,Hsp70.3,Hsp72,Hspa1a,hsp68,hsp70A1
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-TA038-Ag-1/ GM-Tg-hg-TA038-Ag-2 | Human HSP70/HSPA1A protein | Human |
| GM-Tg-rg-TA038-Ag-1/ GM-Tg-rg-TA038-Ag-2 | Rat HSP70/HSPA1A protein | Rat |
| GM-Tg-mg-TA038-Ag-1/ GM-Tg-mg-TA038-Ag-2 | Mouse HSP70/HSPA1A protein | Mouse |
| GM-Tg-cynog-TA038-Ag-1/ GM-Tg-cynog-TA038-Ag-2 | Cynomolgus/Rhesus macaque HSP70/HSPA1A protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-TA038-Ag-1/ GM-Tg-felg-TA038-Ag-2 | Feline HSP70/HSPA1A protein | Feline |
| GM-Tg-cang-TA038-Ag-1/ GM-Tg-cang-TA038-Ag-2 | Canine HSP70/HSPA1A protein | Canine |
| GM-Tg-bovg-TA038-Ag-1/ GM-Tg-bovg-TA038-Ag-2 | Bovine HSP70/HSPA1A protein | Bovine |
| GM-Tg-equg-TA038-Ag-1/ GM-Tg-equg-TA038-Ag-2 | Equine HSP70/HSPA1A protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-TA038-Ag-1/ GM-Tg-hg-TA038-Ag-2;
GM-Tg-rg-TA038-Ag-1/ GM-Tg-rg-TA038-Ag-2;
GM-Tg-mg-TA038-Ag-1/ GM-Tg-mg-TA038-Ag-2; GM-Tg-cynog-TA038-Ag-1/ GM-Tg-cynog-TA038-Ag-2; GM-Tg-felg-TA038-Ag-1/ GM-Tg-felg-TA038-Ag-2; GM-Tg-cang-TA038-Ag-1/ GM-Tg-cang-TA038-Ag-2; GM-Tg-bovg-TA038-Ag-1/ GM-Tg-bovg-TA038-Ag-2; GM-Tg-equg-TA038-Ag-1/ GM-Tg-equg-TA038-Ag-2 |
| Products Name | HSP70/HSPA1A protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | HSP70/HSPA1A |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HSP70/HSPA1A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.