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Target
sublocation: Introcelluar Protein.
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]
| Target ID |
GM-TA038
|
| Target Name |
HSP70/HSPA1A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
3303
|
| Gene ID |
193740 (Mus musculus), 3303 (Homo sapiens), 720054 (Macaca mulatta)
|
| Target Alternative Names |
HEL-S-103,HSP70,HSP70-1,HSP70-1A,HSP70-2,HSP70.1,HSP70.1),HSP70.2,HSP70I,HSP72,HSPA1,HSPA1A,HSPA1B,Heat shock 70 kDa protein 1 (HSP70-1,Heat shock 70 kDa protein 1A,Heat shock protein family A member 1A,Hsp70,Hsp70-3,Hsp70.3,Hsp72,Hspa1a,hsp68,hsp70A1
|
| Uniprot Accession |
Q61696,P0DMV8
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease |
Malignant neoplasm of bladder
|
| Disease from KEGG |
MAPK signaling pathway, Protein processing in endoplasmic reticulum, Longevity regulating pathway - multiple species, Antigen processing and presentation, Legionellosis, Toxoplasmosis, Measles, Lipid and atherosclerosis
|
| Gene Ensembl |
ENSMUSG00000091971, ENSG00000204389
|
Pre-made viral vector of HSP70/HSPA1A cDNA Clones/ORF Plasmid
HSP70/HSPA1A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3303 | Pre-made Human HSPA1A/HSP70/HSP72 siRNA oligo Duplex | 3303 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo193740 | Pre-made Mouse Hspa1a/Hsp72/hsp68 siRNA oligo Duplex | 193740 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo720054 | Pre-made Cynomolgus/Rhesus macaque HSPA1A/Hsp70/HSPA1B siRNA oligo Duplex | 720054 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
HSP70/HSPA1A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA038-Ab | Human | Anti-Human HSP70/HSPA1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA038-Ab | Mouse | Anti-Mouse HSP70/HSPA1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA038-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HSP70/HSPA1A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
HSP70/HSPA1A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA038-Ag | Human | Human HSP70/HSPA1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-TA038-Ag | Mouse | Mouse HSP70/HSPA1A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-TA038-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HSP70/HSPA1A recombinant protein | Mammalian cell | Detail |
