Recombinant multi-species AMPK Alpha 1/AMPK Alpha/PRKAA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AMPK Alpha 1/AMPK Alpha/PRKAA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 5'-AMP-activated protein kinase catalytic subunit alpha-1,AMPK,AMPK Alpha,AMPK Alpha 1,AMPK alpha 1,AMPK subunit alpha-1,AMPKa1,AMPKalpha1,Acetyl-CoA carboxylase kinase (ACACA kinase),C130083N04Rik,Hydroxymethylglutaryl-CoA reductase kinase (HMGCR kinase),PRKAA1,Prkaa1,Tau-protein kinase PRKAA1

Target products collectionGo to AMPK Alpha 1/AMPK Alpha/PRKAA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-TA017-Ag-1/ GM-Tg-hg-TA017-Ag-2 Human AMPK Alpha 1/AMPK Alpha/PRKAA1 protein Human
GM-Tg-rg-TA017-Ag-1/ GM-Tg-rg-TA017-Ag-2 Rat AMPK Alpha 1/AMPK Alpha/PRKAA1 protein Rat
GM-Tg-mg-TA017-Ag-1/ GM-Tg-mg-TA017-Ag-2 Mouse AMPK Alpha 1/AMPK Alpha/PRKAA1 protein Mouse
GM-Tg-cynog-TA017-Ag-1/ GM-Tg-cynog-TA017-Ag-2 Cynomolgus/Rhesus macaque AMPK Alpha 1/AMPK Alpha/PRKAA1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-TA017-Ag-1/ GM-Tg-felg-TA017-Ag-2 Feline AMPK Alpha 1/AMPK Alpha/PRKAA1 protein Feline
GM-Tg-cang-TA017-Ag-1/ GM-Tg-cang-TA017-Ag-2 Canine AMPK Alpha 1/AMPK Alpha/PRKAA1 protein Canine
GM-Tg-bovg-TA017-Ag-1/ GM-Tg-bovg-TA017-Ag-2 Bovine AMPK Alpha 1/AMPK Alpha/PRKAA1 protein Bovine
GM-Tg-equg-TA017-Ag-1/ GM-Tg-equg-TA017-Ag-2 Equine AMPK Alpha 1/AMPK Alpha/PRKAA1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-TA017-Ag-1/ GM-Tg-hg-TA017-Ag-2; GM-Tg-rg-TA017-Ag-1/ GM-Tg-rg-TA017-Ag-2;
GM-Tg-mg-TA017-Ag-1/ GM-Tg-mg-TA017-Ag-2; GM-Tg-cynog-TA017-Ag-1/ GM-Tg-cynog-TA017-Ag-2;
GM-Tg-felg-TA017-Ag-1/ GM-Tg-felg-TA017-Ag-2; GM-Tg-cang-TA017-Ag-1/ GM-Tg-cang-TA017-Ag-2;
GM-Tg-bovg-TA017-Ag-1/ GM-Tg-bovg-TA017-Ag-2; GM-Tg-equg-TA017-Ag-1/ GM-Tg-equg-TA017-Ag-2
Products Name AMPK Alpha 1/AMPK Alpha/PRKAA1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name AMPK Alpha 1/AMPK Alpha/PRKAA1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine AMPK Alpha 1/AMPK Alpha/PRKAA1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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