Recombinant multi-species POLR2A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine POLR2A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 220kDa,3'-5' exoribonuclease,DNA-directed RNA polymerase II subunit A,DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase III largest subunit,NEDHIB,POLR2,POLR2A,POLRA,Polr2a,RNA polymerase II subunit B1,RNA-directed RNA polymerase II subunit RPB1,RPB1,RPBh1,RPO2,RPOL2,RpIILS,Rpb1,Rpo2-1,hRPB220,hsRPB1

Target products collectionGo to POLR2A products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-TA016-Ag-1/ GM-Tg-hg-TA016-Ag-2 Human POLR2A protein Human
GM-Tg-rg-TA016-Ag-1/ GM-Tg-rg-TA016-Ag-2 Rat POLR2A protein Rat
GM-Tg-mg-TA016-Ag-1/ GM-Tg-mg-TA016-Ag-2 Mouse POLR2A protein Mouse
GM-Tg-cynog-TA016-Ag-1/ GM-Tg-cynog-TA016-Ag-2 Cynomolgus/Rhesus macaque POLR2A protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-TA016-Ag-1/ GM-Tg-felg-TA016-Ag-2 Feline POLR2A protein Feline
GM-Tg-cang-TA016-Ag-1/ GM-Tg-cang-TA016-Ag-2 Canine POLR2A protein Canine
GM-Tg-bovg-TA016-Ag-1/ GM-Tg-bovg-TA016-Ag-2 Bovine POLR2A protein Bovine
GM-Tg-equg-TA016-Ag-1/ GM-Tg-equg-TA016-Ag-2 Equine POLR2A protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-TA016-Ag-1/ GM-Tg-hg-TA016-Ag-2; GM-Tg-rg-TA016-Ag-1/ GM-Tg-rg-TA016-Ag-2;
GM-Tg-mg-TA016-Ag-1/ GM-Tg-mg-TA016-Ag-2; GM-Tg-cynog-TA016-Ag-1/ GM-Tg-cynog-TA016-Ag-2;
GM-Tg-felg-TA016-Ag-1/ GM-Tg-felg-TA016-Ag-2; GM-Tg-cang-TA016-Ag-1/ GM-Tg-cang-TA016-Ag-2;
GM-Tg-bovg-TA016-Ag-1/ GM-Tg-bovg-TA016-Ag-2; GM-Tg-equg-TA016-Ag-1/ GM-Tg-equg-TA016-Ag-2
Products Name POLR2A protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name POLR2A
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine POLR2A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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