Explore POLR2A gene products and cross-species
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insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008]
| Target ID |
GM-TA016
|
| Target Name |
POLR2A
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5430
|
| Gene ID |
100072997 (Equus caballus), 101098500 (Felis catus), 20020 (Mus musculus), 282312 (Bos taurus)
363633 (Rattus norvegicus), 479483 (Canis lupus familiaris), 5430 (Homo sapiens), 721865 (Macaca mulatta)
|
| Target Alternative Names |
220kDa,3'-5' exoribonuclease,DNA-directed RNA polymerase II subunit A,DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase III largest subunit,NEDHIB,POLR2,POLR2A,POLRA,Polr2a,RNA polymerase II subunit B1,RNA-directed RNA polymerase II subunit RPB1,RPB1,RPBh1,RPO2,RPOL2,RpIILS,Rpb1,Rpo2-1,hRPB220,hsRPB1
|
| Uniprot Accession |
P08775,G3MZY8,P24928
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSECAG00000018485, ENSMUSG00000005198, ENSBTAG00000046765, ENSCAFG00845022622, ENSG00000181222, ENSMMUG00000023620
|
POLR2A siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5430 | Pre-made Human POLR2A/RPB1/RPO2 siRNA oligo Duplex | 5430 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo363633 | Pre-made Rat Polr2a/Rpo2-1 siRNA oligo Duplex | 363633 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo20020 | Pre-made Mouse Polr2a/Rpb1/220kDa siRNA oligo Duplex | 20020 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo721865 | Pre-made Cynomolgus/Rhesus macaque POLR2A siRNA oligo Duplex | 721865 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101098500 | Pre-made Cat/Feline POLR2A siRNA oligo Duplex | 101098500 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo479483 | Pre-made Dog/Canine POLR2A siRNA oligo Duplex | 479483 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo282312 | Pre-made Bovines/Cattle POLR2A siRNA oligo Duplex | 282312 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100072997 | Pre-made Equine/Horse POLR2A siRNA oligo Duplex | 100072997 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
POLR2A antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-TA016-Ab | Human | Anti-Human POLR2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-TA016-Ab | Rat | Anti-Rat POLR2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-TA016-Ab | Mouse | Anti-Mouse POLR2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-TA016-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque POLR2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-TA016-Ab | Cat/Feline | Anti-Cat/Feline POLR2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-TA016-Ab | Dog/Canine | Anti-Dog/Canine POLR2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-TA016-Ab | Bovines/Cattle | Anti-Bovines/Cattle POLR2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-TA016-Ab | Equine/Horse | Anti-Equine/Horse POLR2A monoclonal antibody | mab | Therapeutics Target antibody | Detail |
POLR2A recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-TA016-Ag | Human | Human POLR2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-TA016-Ag | Rat | Rat POLR2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-TA016-Ag | Mouse | Mouse POLR2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-TA016-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque POLR2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-TA016-Ag | Cat/Feline | Cat/Feline POLR2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-TA016-Ag | Dog/Canine | Dog/Canine POLR2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-TA016-Ag | Bovines/Cattle | Bovines/Cattle POLR2A recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-TA016-Ag | Equine/Horse | Equine/Horse POLR2A recombinant protein | Mammalian cell | Detail |
