Recombinant multi-species FGF18 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FGF18 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures. [provided by RefSeq, Jul 2008]
The Alternative Names of target: D130055P09Rik,FGF-18,FGF18,FGF6A,Fgf18,Fgf6a,Fibroblast growth factor 18,ZFGF5,zFGF5

Target products collectionGo to FGF18 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T99732-Ag-1/ GM-Tg-hg-T99732-Ag-2 Human FGF18 protein Human
GM-Tg-rg-T99732-Ag-1/ GM-Tg-rg-T99732-Ag-2 Rat FGF18 protein Rat
GM-Tg-mg-T99732-Ag-1/ GM-Tg-mg-T99732-Ag-2 Mouse FGF18 protein Mouse
GM-Tg-cynog-T99732-Ag-1/ GM-Tg-cynog-T99732-Ag-2 Cynomolgus/Rhesus macaque FGF18 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T99732-Ag-1/ GM-Tg-felg-T99732-Ag-2 Feline FGF18 protein Feline
GM-Tg-cang-T99732-Ag-1/ GM-Tg-cang-T99732-Ag-2 Canine FGF18 protein Canine
GM-Tg-bovg-T99732-Ag-1/ GM-Tg-bovg-T99732-Ag-2 Bovine FGF18 protein Bovine
GM-Tg-equg-T99732-Ag-1/ GM-Tg-equg-T99732-Ag-2 Equine FGF18 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T99732-Ag-1/ GM-Tg-hg-T99732-Ag-2; GM-Tg-rg-T99732-Ag-1/ GM-Tg-rg-T99732-Ag-2;
GM-Tg-mg-T99732-Ag-1/ GM-Tg-mg-T99732-Ag-2; GM-Tg-cynog-T99732-Ag-1/ GM-Tg-cynog-T99732-Ag-2;
GM-Tg-felg-T99732-Ag-1/ GM-Tg-felg-T99732-Ag-2; GM-Tg-cang-T99732-Ag-1/ GM-Tg-cang-T99732-Ag-2;
GM-Tg-bovg-T99732-Ag-1/ GM-Tg-bovg-T99732-Ag-2; GM-Tg-equg-T99732-Ag-1/ GM-Tg-equg-T99732-Ag-2
Products Name FGF18 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name FGF18
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FGF18 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.