Recombinant multi-species PDK3/PDHK3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDK3/PDHK3 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]
The Alternative Names of target: 2610001M10Rik,CMTX6,GS1-358P8.4,PDHK3,PDK3,Pdk3,Pyruvate dehydrogenase kinase isoform 3,[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3,mitochondrial

Target products collectionGo to PDK3/PDHK3 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T99029-Ag-1/ GM-Tg-hg-T99029-Ag-2 Human PDK3/PDHK3 protein Human
GM-Tg-rg-T99029-Ag-1/ GM-Tg-rg-T99029-Ag-2 Rat PDK3/PDHK3 protein Rat
GM-Tg-mg-T99029-Ag-1/ GM-Tg-mg-T99029-Ag-2 Mouse PDK3/PDHK3 protein Mouse
GM-Tg-cynog-T99029-Ag-1/ GM-Tg-cynog-T99029-Ag-2 Cynomolgus/Rhesus macaque PDK3/PDHK3 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T99029-Ag-1/ GM-Tg-felg-T99029-Ag-2 Feline PDK3/PDHK3 protein Feline
GM-Tg-cang-T99029-Ag-1/ GM-Tg-cang-T99029-Ag-2 Canine PDK3/PDHK3 protein Canine
GM-Tg-bovg-T99029-Ag-1/ GM-Tg-bovg-T99029-Ag-2 Bovine PDK3/PDHK3 protein Bovine
GM-Tg-equg-T99029-Ag-1/ GM-Tg-equg-T99029-Ag-2 Equine PDK3/PDHK3 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T99029-Ag-1/ GM-Tg-hg-T99029-Ag-2; GM-Tg-rg-T99029-Ag-1/ GM-Tg-rg-T99029-Ag-2;
GM-Tg-mg-T99029-Ag-1/ GM-Tg-mg-T99029-Ag-2; GM-Tg-cynog-T99029-Ag-1/ GM-Tg-cynog-T99029-Ag-2;
GM-Tg-felg-T99029-Ag-1/ GM-Tg-felg-T99029-Ag-2; GM-Tg-cang-T99029-Ag-1/ GM-Tg-cang-T99029-Ag-2;
GM-Tg-bovg-T99029-Ag-1/ GM-Tg-bovg-T99029-Ag-2; GM-Tg-equg-T99029-Ag-1/ GM-Tg-equg-T99029-Ag-2
Products Name PDK3/PDHK3 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PDK3/PDHK3
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDK3/PDHK3 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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