PDK3/PDHK3 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore PDK3/PDHK3 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Target ID GM-T99029
Target Name PDK3/PDHK3
Gene Group ldentifer
(Target Gene ID in Homo species)
5165
Gene ID 100060791 (Equus caballus), 101095314 (Felis catus), 119868412 (Canis lupus familiaris), 236900 (Mus musculus)
296849 (Rattus norvegicus), 510841 (Bos taurus), 5165 (Homo sapiens), 699394 (Macaca mulatta)
Target Alternative Names 2610001M10Rik,CMTX6,GS1-358P8.4,PDHK3,PDK3,Pdk3,Pyruvate dehydrogenase kinase isoform 3,[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3,mitochondrial
Uniprot Accession Q922H2,Q15120
Protein Sub-location Introcelluar Protein
Category Therapeutics Target
Gene Ensembl ENSECAG00000010080, ENSCAFG00845030590, ENSMUSG00000035232, ENSBTAG00000017832, ENSG00000067992, ENSMMUG00000012819


Pre-made viral vector of PDK3/PDHK3 cDNA Clones/ORF Plasmid

Cat No.Product NameNMIDGeneIDSpeciesTypeMarkerFusion TagPromoterDetail
pGMLP005508Human PDK3/CMTX6/GS1-358P8.4 Lentivirus plasmidNM_005391.45165HumanLentivirus plasmidZsGreen3xflag (C-Terminal)CMVDetail
vGMLP005508Human PDK3/CMTX6/GS1-358P8.4 Lentivirus particleNM_005391.45165HumanLentivirus particleZsGreen3xflag (C-Terminal)CMVDetail


PDK3/PDHK3 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.Product NameGeneIDSpeciesGradeDetail
pGMoligo5165Pre-made Human PDK3/CMTX6/GS1-358P8.4 siRNA oligo Duplex5165HumanIn-vitro grade; in-vivo gradeDetail
pGMoligo296849Pre-made Rat Pdk3 siRNA oligo Duplex296849RatIn-vitro grade; in-vivo gradeDetail
pGMoligo236900Pre-made Mouse Pdk3/2610001M10Rik siRNA oligo Duplex236900MouseIn-vitro grade; in-vivo gradeDetail
pGMoligo699394Pre-made Cynomolgus/Rhesus macaque PDK3 siRNA oligo Duplex699394Cynomolgus/Rhesus macaqueIn-vitro grade; in-vivo gradeDetail
pGMoligo101095314Pre-made Cat/Feline PDK3 siRNA oligo Duplex101095314Cat/FelineIn-vitro grade; in-vivo gradeDetail
pGMoligo119868412Pre-made Dog/Canine PDK3 siRNA oligo Duplex119868412Dog/CanineIn-vitro grade; in-vivo gradeDetail
pGMoligo510841Pre-made Bovines/Cattle PDK3 siRNA oligo Duplex510841Bovines/CattleIn-vitro grade; in-vivo gradeDetail
pGMoligo100060791Pre-made Equine/Horse PDK3 siRNA oligo Duplex100060791Equine/HorseIn-vitro grade; in-vivo gradeDetail


PDK3/PDHK3 antibody/GMab

Cat No.SpeciesAntibody NameFormatClassified by tagDetail
GM-Tg-hg-T99029-AbHumanAnti-Human PDK3/PDHK3 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-rg-T99029-AbRatAnti-Rat PDK3/PDHK3 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-mg-T99029-AbMouseAnti-Mouse PDK3/PDHK3 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cynog-T99029-AbCynomolgus/Rhesus macaqueAnti-Cynomolgus/Rhesus macaque PDK3/PDHK3 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-felg-T99029-AbCat/FelineAnti-Cat/Feline PDK3/PDHK3 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-cang-T99029-AbDog/CanineAnti-Dog/Canine PDK3/PDHK3 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-bovg-T99029-AbBovines/CattleAnti-Bovines/Cattle PDK3/PDHK3 monoclonal antibodymabTherapeutics Target antibodyDetail
GM-Tg-equg-T99029-AbEquine/HorseAnti-Equine/Horse PDK3/PDHK3 monoclonal antibodymabTherapeutics Target antibodyDetail


PDK3/PDHK3 recombinant protein

Cat No.SpeciesAntigen NameExpression PlatformDetail
GM-Tg-hg-T99029-AgHumanHuman PDK3/PDHK3 recombinant proteinMammalian cellDetail
GM-Tg-rg-T99029-AgRatRat PDK3/PDHK3 recombinant proteinMammalian cellDetail
GM-Tg-mg-T99029-AgMouseMouse PDK3/PDHK3 recombinant proteinMammalian cellDetail
GM-Tg-cynog-T99029-AgCynomolgus/Rhesus macaqueCynomolgus/Rhesus macaque PDK3/PDHK3 recombinant proteinMammalian cellDetail
GM-Tg-felg-T99029-AgCat/FelineCat/Feline PDK3/PDHK3 recombinant proteinMammalian cellDetail
GM-Tg-cang-T99029-AgDog/CanineDog/Canine PDK3/PDHK3 recombinant proteinMammalian cellDetail
GM-Tg-bovg-T99029-AgBovines/CattleBovines/Cattle PDK3/PDHK3 recombinant proteinMammalian cellDetail
GM-Tg-equg-T99029-AgEquine/HorseEquine/Horse PDK3/PDHK3 recombinant proteinMammalian cellDetail