Recombinant multi-species Thyroid Hormone Receptor beta/THRB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Thyroid Hormone Receptor beta/THRB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
The Alternative Names of target: C-ERBA-2,C-ERBA-BETA,C-erba-beta,ERBA2,GRTH,NR1A2,Nr1a2,Nuclear receptor subfamily 1 group A member 2,PRTH,RATT3REC,T3R[b],T3Rbeta,T3rec,THR,THR1,THRB,THRB1,THRB2,THRbeta,THRbeta1,TRb,TRbeta,TRbeta1,Thrb,Thrb1,Thrb2,Thrbeta2,Thyroid Hormone Receptor beta,Thyroid hormone receptor beta,c-erbA-2,c-erbA-beta,c-erbAbeta

Target products collectionGo to Thyroid Hormone Receptor beta/THRB products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T98933-Ag-1/ GM-Tg-hg-T98933-Ag-2 Human Thyroid Hormone Receptor beta/THRB protein Human
GM-Tg-rg-T98933-Ag-1/ GM-Tg-rg-T98933-Ag-2 Rat Thyroid Hormone Receptor beta/THRB protein Rat
GM-Tg-mg-T98933-Ag-1/ GM-Tg-mg-T98933-Ag-2 Mouse Thyroid Hormone Receptor beta/THRB protein Mouse
GM-Tg-cynog-T98933-Ag-1/ GM-Tg-cynog-T98933-Ag-2 Cynomolgus/Rhesus macaque Thyroid Hormone Receptor beta/THRB protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T98933-Ag-1/ GM-Tg-felg-T98933-Ag-2 Feline Thyroid Hormone Receptor beta/THRB protein Feline
GM-Tg-cang-T98933-Ag-1/ GM-Tg-cang-T98933-Ag-2 Canine Thyroid Hormone Receptor beta/THRB protein Canine
GM-Tg-bovg-T98933-Ag-1/ GM-Tg-bovg-T98933-Ag-2 Bovine Thyroid Hormone Receptor beta/THRB protein Bovine
GM-Tg-equg-T98933-Ag-1/ GM-Tg-equg-T98933-Ag-2 Equine Thyroid Hormone Receptor beta/THRB protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T98933-Ag-1/ GM-Tg-hg-T98933-Ag-2; GM-Tg-rg-T98933-Ag-1/ GM-Tg-rg-T98933-Ag-2;
GM-Tg-mg-T98933-Ag-1/ GM-Tg-mg-T98933-Ag-2; GM-Tg-cynog-T98933-Ag-1/ GM-Tg-cynog-T98933-Ag-2;
GM-Tg-felg-T98933-Ag-1/ GM-Tg-felg-T98933-Ag-2; GM-Tg-cang-T98933-Ag-1/ GM-Tg-cang-T98933-Ag-2;
GM-Tg-bovg-T98933-Ag-1/ GM-Tg-bovg-T98933-Ag-2; GM-Tg-equg-T98933-Ag-1/ GM-Tg-equg-T98933-Ag-2
Products Name Thyroid Hormone Receptor beta/THRB protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Thyroid Hormone Receptor beta/THRB
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Thyroid Hormone Receptor beta/THRB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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