Recombinant multi-species PTH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PTH protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
The Alternative Names of target: FIH1,PTH,PTH-(1-84),PTH1,Parathormone,Parathyrin,Parathyroid hormone,Pth,Pth1,Pthp,Pthr1

Target products collectionGo to PTH products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T98708-Ag-1/ GM-Tg-hg-T98708-Ag-2 Human PTH protein Human
GM-Tg-rg-T98708-Ag-1/ GM-Tg-rg-T98708-Ag-2 Rat PTH protein Rat
GM-Tg-mg-T98708-Ag-1/ GM-Tg-mg-T98708-Ag-2 Mouse PTH protein Mouse
GM-Tg-cynog-T98708-Ag-1/ GM-Tg-cynog-T98708-Ag-2 Cynomolgus/Rhesus macaque PTH protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T98708-Ag-1/ GM-Tg-felg-T98708-Ag-2 Feline PTH protein Feline
GM-Tg-cang-T98708-Ag-1/ GM-Tg-cang-T98708-Ag-2 Canine PTH protein Canine
GM-Tg-bovg-T98708-Ag-1/ GM-Tg-bovg-T98708-Ag-2 Bovine PTH protein Bovine
GM-Tg-equg-T98708-Ag-1/ GM-Tg-equg-T98708-Ag-2 Equine PTH protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T98708-Ag-1/ GM-Tg-hg-T98708-Ag-2; GM-Tg-rg-T98708-Ag-1/ GM-Tg-rg-T98708-Ag-2;
GM-Tg-mg-T98708-Ag-1/ GM-Tg-mg-T98708-Ag-2; GM-Tg-cynog-T98708-Ag-1/ GM-Tg-cynog-T98708-Ag-2;
GM-Tg-felg-T98708-Ag-1/ GM-Tg-felg-T98708-Ag-2; GM-Tg-cang-T98708-Ag-1/ GM-Tg-cang-T98708-Ag-2;
GM-Tg-bovg-T98708-Ag-1/ GM-Tg-bovg-T98708-Ag-2; GM-Tg-equg-T98708-Ag-1/ GM-Tg-equg-T98708-Ag-2
Products Name PTH protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PTH
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PTH protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.