Explore PTH gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
| Target ID |
GM-T98708
|
| Target Name |
PTH
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
5741
|
| Gene ID |
100034104 (Equus caballus), 19226 (Mus musculus), 24694 (Rattus norvegicus), 280903 (Bos taurus)
403986 (Canis lupus familiaris), 493684 (Felis catus), 5741 (Homo sapiens), 700195 (Macaca mulatta)
|
| Target Alternative Names |
FIH1,PTH,PTH-(1-84),PTH1,Parathormone,Parathyrin,Parathyroid hormone,Pth,Pth1,Pthp,Pthr1
|
| Uniprot Accession |
Q27IM2,P04089,P01268,P52212,Q9GL67,P01270
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target, Diagnostics Biomarker
|
| Disease from KEGG |
Neuroactive ligand-receptor interaction, Parathyroid hormone synthesis, secretion and action, Rheumatoid arthritis
|
| Gene Ensembl |
ENSECAG00000019608, ENSMUSG00000059077, ENSBTAG00000019080, ENSCAFG00845020842, ENSG00000152266, ENSMMUG00000054213
|
Pre-made viral vector of PTH cDNA Clones/ORF Plasmid
PTH siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo5741 | Pre-made Human PTH/FIH1/PTH1 siRNA oligo Duplex | 5741 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo24694 | Pre-made Rat Pth/Pth1/Pthr1 siRNA oligo Duplex | 24694 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo19226 | Pre-made Mouse Pth/Pthp siRNA oligo Duplex | 19226 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo700195 | Pre-made Cynomolgus/Rhesus macaque PTH siRNA oligo Duplex | 700195 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo493684 | Pre-made Cat/Feline PTH siRNA oligo Duplex | 493684 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo403986 | Pre-made Dog/Canine PTH siRNA oligo Duplex | 403986 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280903 | Pre-made Bovines/Cattle PTH siRNA oligo Duplex | 280903 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034104 | Pre-made Equine/Horse PTH siRNA oligo Duplex | 100034104 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PTH antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T98708-Ab | Human | Anti-Human PTH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-rg-T98708-Ab | Rat | Anti-Rat PTH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-mg-T98708-Ab | Mouse | Anti-Mouse PTH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-cynog-T98708-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PTH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-felg-T98708-Ab | Cat/Feline | Anti-Cat/Feline PTH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-cang-T98708-Ab | Dog/Canine | Anti-Dog/Canine PTH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-bovg-T98708-Ab | Bovines/Cattle | Anti-Bovines/Cattle PTH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
| GM-Tg-equg-T98708-Ab | Equine/Horse | Anti-Equine/Horse PTH monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody, Diagnostic target antibody | Detail |
PTH recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T98708-Ag | Human | Human PTH recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T98708-Ag | Rat | Rat PTH recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T98708-Ag | Mouse | Mouse PTH recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T98708-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PTH recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T98708-Ag | Cat/Feline | Cat/Feline PTH recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T98708-Ag | Dog/Canine | Dog/Canine PTH recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T98708-Ag | Bovines/Cattle | Bovines/Cattle PTH recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T98708-Ag | Equine/Horse | Equine/Horse PTH recombinant protein | Mammalian cell | Detail |
