Recombinant multi-species PTPN6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PTPN6 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
The Alternative Names of target: 70Z-SHP,DRPLA,HCP,HCPH,HPTP1C,Hcph,Hematopoietic cell protein-tyrosine phosphatase,PTP-1C,PTPN6,PTPTY-42,Protein-tyrosine phosphatase 1C (PTP-1C),Protein-tyrosine phosphatase SHP-1,Ptp1C,Ptph6,Ptpn6,SH-PTP1,SHP-1,SHP-1L,SHP1,Shp-1,Tyrosine-protein phosphatase non-receptor type 6,hcp,me

Target products collectionGo to PTPN6 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T98264-Ag-1/ GM-Tg-hg-T98264-Ag-2 Human PTPN6 protein Human
GM-Tg-rg-T98264-Ag-1/ GM-Tg-rg-T98264-Ag-2 Rat PTPN6 protein Rat
GM-Tg-mg-T98264-Ag-1/ GM-Tg-mg-T98264-Ag-2 Mouse PTPN6 protein Mouse
GM-Tg-cynog-T98264-Ag-1/ GM-Tg-cynog-T98264-Ag-2 Cynomolgus/Rhesus macaque PTPN6 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T98264-Ag-1/ GM-Tg-felg-T98264-Ag-2 Feline PTPN6 protein Feline
GM-Tg-cang-T98264-Ag-1/ GM-Tg-cang-T98264-Ag-2 Canine PTPN6 protein Canine
GM-Tg-bovg-T98264-Ag-1/ GM-Tg-bovg-T98264-Ag-2 Bovine PTPN6 protein Bovine
GM-Tg-equg-T98264-Ag-1/ GM-Tg-equg-T98264-Ag-2 Equine PTPN6 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T98264-Ag-1/ GM-Tg-hg-T98264-Ag-2; GM-Tg-rg-T98264-Ag-1/ GM-Tg-rg-T98264-Ag-2;
GM-Tg-mg-T98264-Ag-1/ GM-Tg-mg-T98264-Ag-2; GM-Tg-cynog-T98264-Ag-1/ GM-Tg-cynog-T98264-Ag-2;
GM-Tg-felg-T98264-Ag-1/ GM-Tg-felg-T98264-Ag-2; GM-Tg-cang-T98264-Ag-1/ GM-Tg-cang-T98264-Ag-2;
GM-Tg-bovg-T98264-Ag-1/ GM-Tg-bovg-T98264-Ag-2; GM-Tg-equg-T98264-Ag-1/ GM-Tg-equg-T98264-Ag-2
Products Name PTPN6 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PTPN6
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PTPN6 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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