Recombinant multi-species HK2/Hexokinase 2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HK2/Hexokinase 2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009]
The Alternative Names of target: HK2,HKII,HXK2,Hexokinase 2,Hexokinase type II (HK II),Hexokinase-2,Hexokinase-B,Hk2,Muscle form hexokinase

Target products collectionGo to HK2/Hexokinase 2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T96685-Ag-1/ GM-Tg-hg-T96685-Ag-2 Human HK2/Hexokinase 2 protein Human
GM-Tg-rg-T96685-Ag-1/ GM-Tg-rg-T96685-Ag-2 Rat HK2/Hexokinase 2 protein Rat
GM-Tg-mg-T96685-Ag-1/ GM-Tg-mg-T96685-Ag-2 Mouse HK2/Hexokinase 2 protein Mouse
GM-Tg-cynog-T96685-Ag-1/ GM-Tg-cynog-T96685-Ag-2 Cynomolgus/Rhesus macaque HK2/Hexokinase 2 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T96685-Ag-1/ GM-Tg-felg-T96685-Ag-2 Feline HK2/Hexokinase 2 protein Feline
GM-Tg-cang-T96685-Ag-1/ GM-Tg-cang-T96685-Ag-2 Canine HK2/Hexokinase 2 protein Canine
GM-Tg-bovg-T96685-Ag-1/ GM-Tg-bovg-T96685-Ag-2 Bovine HK2/Hexokinase 2 protein Bovine
GM-Tg-equg-T96685-Ag-1/ GM-Tg-equg-T96685-Ag-2 Equine HK2/Hexokinase 2 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T96685-Ag-1/ GM-Tg-hg-T96685-Ag-2; GM-Tg-rg-T96685-Ag-1/ GM-Tg-rg-T96685-Ag-2;
GM-Tg-mg-T96685-Ag-1/ GM-Tg-mg-T96685-Ag-2; GM-Tg-cynog-T96685-Ag-1/ GM-Tg-cynog-T96685-Ag-2;
GM-Tg-felg-T96685-Ag-1/ GM-Tg-felg-T96685-Ag-2; GM-Tg-cang-T96685-Ag-1/ GM-Tg-cang-T96685-Ag-2;
GM-Tg-bovg-T96685-Ag-1/ GM-Tg-bovg-T96685-Ag-2; GM-Tg-equg-T96685-Ag-1/ GM-Tg-equg-T96685-Ag-2
Products Name HK2/Hexokinase 2 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name HK2/Hexokinase 2
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HK2/Hexokinase 2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.