Explore HK2/Hexokinase 2 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Introcelluar Protein.
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. [provided by RefSeq, Apr 2009]
| Target ID |
GM-T96685
|
| Target Name |
HK2/Hexokinase 2
|
Gene Group ldentifer (Target Gene ID in Homo
species)
|
3099
|
| Gene ID |
100009677 (Equus caballus), 100856448 (Canis lupus familiaris), 101089344 (Felis catus), 15277 (Mus musculus) 25059 (Rattus norvegicus), 3099 (Homo sapiens), 710479 (Macaca mulatta), 788926 (Bos taurus)
|
| Target Alternative Names |
HK2,HKII,HXK2,Hexokinase 2,Hexokinase type II (HK II),Hexokinase-2,Hexokinase-B,Hk2,Muscle form hexokinase
|
| Uniprot Accession |
A2PYL6,O08528,P27881,P52789
|
| Protein Sub-location |
Introcelluar Protein
|
| Category |
Therapeutics Target
|
| Disease from KEGG |
Metabolic pathways, HIF-1 signaling pathway, Type II diabetes mellitus, Carbohydrate digestion and absorption, Central carbon metabolism in cancer
|
| Gene Ensembl |
ENSECAG00000021905, ENSCAFG00845016792, ENSMUSG00000000628, ENSG00000159399, ENSMMUG00000011845, ENSBTAG00000013108
|
Pre-made viral vector of HK2/Hexokinase 2 cDNA Clones/ORF Plasmid
HK2/Hexokinase 2 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo3099 | Pre-made Human HK2/HKII/HXK2 siRNA oligo Duplex | 3099 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo25059 | Pre-made Rat Hk2 siRNA oligo Duplex | 25059 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo15277 | Pre-made Mouse Hk2/HKII siRNA oligo Duplex | 15277 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo710479 | Pre-made Cynomolgus/Rhesus macaque HK2 siRNA oligo Duplex | 710479 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101089344 | Pre-made Cat/Feline HK2 siRNA oligo Duplex | 101089344 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100856448 | Pre-made Dog/Canine HK2 siRNA oligo Duplex | 100856448 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo788926 | Pre-made Bovines/Cattle HK2 siRNA oligo Duplex | 788926 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100009677 | Pre-made Equine/Horse HK2/HKII siRNA oligo Duplex | 100009677 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
HK2/Hexokinase 2 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T96685-Ab | Human | Anti-Human HK2/Hexokinase 2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-rg-T96685-Ab | Rat | Anti-Rat HK2/Hexokinase 2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-mg-T96685-Ab | Mouse | Anti-Mouse HK2/Hexokinase 2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T96685-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque HK2/Hexokinase 2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-felg-T96685-Ab | Cat/Feline | Anti-Cat/Feline HK2/Hexokinase 2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-cang-T96685-Ab | Dog/Canine | Anti-Dog/Canine HK2/Hexokinase 2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T96685-Ab | Bovines/Cattle | Anti-Bovines/Cattle HK2/Hexokinase 2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
| GM-Tg-equg-T96685-Ab | Equine/Horse | Anti-Equine/Horse HK2/Hexokinase 2 monoclonal antibody | mab | Therapeutics Target antibody | Detail |
HK2/Hexokinase 2 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T96685-Ag | Human | Human HK2/Hexokinase 2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T96685-Ag | Rat | Rat HK2/Hexokinase 2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T96685-Ag | Mouse | Mouse HK2/Hexokinase 2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T96685-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque HK2/Hexokinase 2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T96685-Ag | Cat/Feline | Cat/Feline HK2/Hexokinase 2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T96685-Ag | Dog/Canine | Dog/Canine HK2/Hexokinase 2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T96685-Ag | Bovines/Cattle | Bovines/Cattle HK2/Hexokinase 2 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T96685-Ag | Equine/Horse | Equine/Horse HK2/Hexokinase 2 recombinant protein | Mammalian cell | Detail |