Recombinant multi-species CXCL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CXCL1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4. [provided by RefSeq, Sep 2014]
The Alternative Names of target: C-X-C motif chemokine 1,CXCL1,FSP,GRO-alpha(1-73),GRO1,GROa,Growth-regulated alpha protein,MGSA,MGSA-a,Melanoma growth stimulatory activity (MGSA),NAP-3,Neutrophil-activating protein 3 (NAP-3),SCYB1

Target products collectionGo to CXCL1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T96005-Ag-1/ GM-Tg-hg-T96005-Ag-2 Human CXCL1 protein Human
GM-Tg-rg-T96005-Ag-1/ GM-Tg-rg-T96005-Ag-2 Rat CXCL1 protein Rat
GM-Tg-mg-T96005-Ag-1/ GM-Tg-mg-T96005-Ag-2 Mouse CXCL1 protein Mouse
GM-Tg-cynog-T96005-Ag-1/ GM-Tg-cynog-T96005-Ag-2 Cynomolgus/Rhesus macaque CXCL1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T96005-Ag-1/ GM-Tg-felg-T96005-Ag-2 Feline CXCL1 protein Feline
GM-Tg-cang-T96005-Ag-1/ GM-Tg-cang-T96005-Ag-2 Canine CXCL1 protein Canine
GM-Tg-bovg-T96005-Ag-1/ GM-Tg-bovg-T96005-Ag-2 Bovine CXCL1 protein Bovine
GM-Tg-equg-T96005-Ag-1/ GM-Tg-equg-T96005-Ag-2 Equine CXCL1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T96005-Ag-1/ GM-Tg-hg-T96005-Ag-2; GM-Tg-rg-T96005-Ag-1/ GM-Tg-rg-T96005-Ag-2;
GM-Tg-mg-T96005-Ag-1/ GM-Tg-mg-T96005-Ag-2; GM-Tg-cynog-T96005-Ag-1/ GM-Tg-cynog-T96005-Ag-2;
GM-Tg-felg-T96005-Ag-1/ GM-Tg-felg-T96005-Ag-2; GM-Tg-cang-T96005-Ag-1/ GM-Tg-cang-T96005-Ag-2;
GM-Tg-bovg-T96005-Ag-1/ GM-Tg-bovg-T96005-Ag-2; GM-Tg-equg-T96005-Ag-1/ GM-Tg-equg-T96005-Ag-2
Products Name CXCL1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CXCL1
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CXCL1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






    About Gmab

    GDU
    GDU

    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
    Through expression in mammalian cell lines, GMab has been established as a paradigmatic reference antibody. It holds significance in myriad domains of biological drug discovery, encompassing cellular cultivation, innovative assay methodologies, strategic animal model systematization, in-depth pharmacokinetic & pharmacodynamic (PK/PD) modeling, and intricate mechanism of action (MOA) investigations.