Recombinant multi-species TWIST1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TWIST1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a basic helix-loop-helix (bHLH) transcription factor that plays an important role in embryonic development. The encoded protein forms both homodimers and heterodimers that bind to DNA E box sequences and regulate the transcription of genes involved in cranial suture closure during skull development. This protein may also regulate neural tube closure, limb development and brown fat metabolism. This gene is hypermethylated and overexpressed in multiple human cancers, and the encoded protein promotes tumor cell invasion and metastasis, as well as metastatic recurrence. Mutations in this gene cause Saethre-Chotzen syndrome in human patients, which is characterized by craniosynostosis, ptosis and hypertelorism. [provided by RefSeq, Jul 2020]
The Alternative Names of target: ACS3,BPES2,BPES3,CRS,CRS1,CSO,Class A basic helix-loop-helix protein 38 (bHLHa38),H-twist,M-Twist,Pde,SCS,SWCOS,Ska10,Ska,TWIST,TWIST1,Twist,Twist-related protein 1,Twist1,bHLHa38,pdt

Target products collectionGo to TWIST1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T95660-Ag-1/ GM-Tg-hg-T95660-Ag-2 Human TWIST1 protein Human
GM-Tg-rg-T95660-Ag-1/ GM-Tg-rg-T95660-Ag-2 Rat TWIST1 protein Rat
GM-Tg-mg-T95660-Ag-1/ GM-Tg-mg-T95660-Ag-2 Mouse TWIST1 protein Mouse
GM-Tg-cynog-T95660-Ag-1/ GM-Tg-cynog-T95660-Ag-2 Cynomolgus/Rhesus macaque TWIST1 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T95660-Ag-1/ GM-Tg-felg-T95660-Ag-2 Feline TWIST1 protein Feline
GM-Tg-cang-T95660-Ag-1/ GM-Tg-cang-T95660-Ag-2 Canine TWIST1 protein Canine
GM-Tg-bovg-T95660-Ag-1/ GM-Tg-bovg-T95660-Ag-2 Bovine TWIST1 protein Bovine
GM-Tg-equg-T95660-Ag-1/ GM-Tg-equg-T95660-Ag-2 Equine TWIST1 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T95660-Ag-1/ GM-Tg-hg-T95660-Ag-2; GM-Tg-rg-T95660-Ag-1/ GM-Tg-rg-T95660-Ag-2;
GM-Tg-mg-T95660-Ag-1/ GM-Tg-mg-T95660-Ag-2; GM-Tg-cynog-T95660-Ag-1/ GM-Tg-cynog-T95660-Ag-2;
GM-Tg-felg-T95660-Ag-1/ GM-Tg-felg-T95660-Ag-2; GM-Tg-cang-T95660-Ag-1/ GM-Tg-cang-T95660-Ag-2;
GM-Tg-bovg-T95660-Ag-1/ GM-Tg-bovg-T95660-Ag-2; GM-Tg-equg-T95660-Ag-1/ GM-Tg-equg-T95660-Ag-2
Products Name TWIST1 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name TWIST1
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TWIST1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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