Recombinant multi-species NEDD4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NEDD4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. [provided by RefSeq, Jul 2016]
The Alternative Names of target: NEDD4,E3 ubiquitin-protein ligase NEDD4,Cell proliferation-inducing gene 53 protein, HECT-type E3 ubiquitin transferase NEDD4, Neural precursor cell expressed developmentally down-regulated protein 4 (NEDD-4),RPF1,NEDD4-1

Target products collectionGo to NEDD4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T94980-Ab-1/ GM-Tg-hg-T94980-Ab-2 Human NEDD4 protein Human
GM-Tg-rg-T94980-Ab-1/ GM-Tg-rg-T94980-Ab-2 Rat NEDD4 protein Rat
GM-Tg-mg-T94980-Ab-1/ GM-Tg-mg-T94980-Ab-2 Mouse NEDD4 protein Mouse
GM-Tg-cynog-T94980-Ab-1/ GM-Tg-cynog-T94980-Ab-2 Cynomolgus/Rhesus macaque NEDD4 monoclonal antibody Cynomolgus/ Rhesus macaque
GM-Tg-felg-T94980-Ab-1/ GM-Tg-felg-T94980-Ab-2 Feline NEDD4 protein Feline
GM-Tg-cang-T94980-Ab-1/ GM-Tg-cang-T94980-Ab-2 Canine NEDD4 protein Canine
GM-Tg-bovg-T94980-Ab-1/ GM-Tg-bovg-T94980-Ab-2 Bovine NEDD4 protein Bovine
GM-Tg-equg-T94980-Ab-1/ GM-Tg-equg-T94980-Ab-2 Equine NEDD4 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T94980-Ab-1/ GM-Tg-hg-T94980-Ab-2; GM-Tg-rg-T94980-Ab-1/ GM-Tg-rg-T94980-Ab-2;
GM-Tg-mg-T94980-Ab-1/ GM-Tg-mg-T94980-Ab-2; GM-Tg-cynog-T94980-Ab-1/ GM-Tg-cynog-T94980-Ab-2;
GM-Tg-felg-T94980-Ab-1/ GM-Tg-felg-T94980-Ab-2; GM-Tg-cang-T94980-Ab-1/ GM-Tg-cang-T94980-Ab-2;
GM-Tg-bovg-T94980-Ab-1/ GM-Tg-bovg-T94980-Ab-2; GM-Tg-equg-T94980-Ab-1/ GM-Tg-equg-T94980-Ab-2
Products Name NEDD4 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name NEDD4
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NEDD4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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