Recombinant multi-species PRG4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRG4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a large proteoglycan that is synthesized by chondrocytes located at the surface of articular cartilage and by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
The Alternative Names of target: CACP,DOL54,HAPO,JCAP,Lubricin,MSF,Megakaryocyte-stimulating factor,PRG4,Prg4,Proteoglycan 4,SZP,Superficial zone proteoglycan,lubricin

Target products collectionGo to PRG4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

pdfMSDSpdfCOApdfDatasheet

Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T94942-Ag-1/ GM-Tg-hg-T94942-Ag-2 Human PRG4 protein Human
GM-Tg-rg-T94942-Ag-1/ GM-Tg-rg-T94942-Ag-2 Rat PRG4 protein Rat
GM-Tg-mg-T94942-Ag-1/ GM-Tg-mg-T94942-Ag-2 Mouse PRG4 protein Mouse
GM-Tg-cynog-T94942-Ag-1/ GM-Tg-cynog-T94942-Ag-2 Cynomolgus/Rhesus macaque PRG4 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T94942-Ag-1/ GM-Tg-felg-T94942-Ag-2 Feline PRG4 protein Feline
GM-Tg-cang-T94942-Ag-1/ GM-Tg-cang-T94942-Ag-2 Canine PRG4 protein Canine
GM-Tg-bovg-T94942-Ag-1/ GM-Tg-bovg-T94942-Ag-2 Bovine PRG4 protein Bovine
GM-Tg-equg-T94942-Ag-1/ GM-Tg-equg-T94942-Ag-2 Equine PRG4 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T94942-Ag-1/ GM-Tg-hg-T94942-Ag-2; GM-Tg-rg-T94942-Ag-1/ GM-Tg-rg-T94942-Ag-2;
GM-Tg-mg-T94942-Ag-1/ GM-Tg-mg-T94942-Ag-2; GM-Tg-cynog-T94942-Ag-1/ GM-Tg-cynog-T94942-Ag-2;
GM-Tg-felg-T94942-Ag-1/ GM-Tg-felg-T94942-Ag-2; GM-Tg-cang-T94942-Ag-1/ GM-Tg-cang-T94942-Ag-2;
GM-Tg-bovg-T94942-Ag-1/ GM-Tg-bovg-T94942-Ag-2; GM-Tg-equg-T94942-Ag-1/ GM-Tg-equg-T94942-Ag-2
Products Name PRG4 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name PRG4
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PRG4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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