Explore PRG4 gene products and cross-species
research data at TarMart platform. Discover comprehensive
biological information, expression tools, and therapeutic
insights for Homo sapiens (human), Cynomolgus monkeys, rodents
(mouse/rat), canines, felines, bovines, and equines. Your
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Target
sublocation: Secreted Protein/Potential Cytokines.
The protein encoded by this gene is a large proteoglycan that is synthesized by chondrocytes located at the surface of articular cartilage and by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
| Target ID |
GM-T94942
|
| Target Name |
PRG4
|
Gene Group ldentifer
（Target Gene ID in Homo
species)
|
10216
|
| Gene ID |
100034016 (Equus caballus), 101085684 (Felis catus), 10216 (Homo sapiens), 280867 (Bos taurus)
289104 (Rattus norvegicus), 664716 (Canis lupus familiaris), 716849 (Macaca mulatta), 96875 (Mus musculus)
|
| Target Alternative Names |
CACP,DOL54,HAPO,JCAP,Lubricin,MSF,Megakaryocyte-stimulating factor,PRG4,Prg4,Proteoglycan 4,SZP,Superficial zone proteoglycan,lubricin
|
| Uniprot Accession |
Q92954,Q9JM99
|
| Protein Sub-location |
Secreted Protein/Potential Cytokines
|
| Category |
Therapeutics Target
|
| Gene Ensembl |
ENSG00000116690, ENSBTAG00000011932, ENSMMUG00000009076, ENSMUSG00000006014
|
PRG4 siRNA/miRNA/oligo for RNA interfence (RNAi)
| Cat No. | Product Name | GeneID | Species | Grade | Detail |
|---|
| pGMoligo10216 | Pre-made Human PRG4/MSF/SZP siRNA oligo Duplex | 10216 | Human | In-vitro grade; in-vivo grade | Detail |
| pGMoligo289104 | Pre-made Rat Prg4 siRNA oligo Duplex | 289104 | Rat | In-vitro grade; in-vivo grade | Detail |
| pGMoligo96875 | Pre-made Mouse Prg4/MSF/SZP siRNA oligo Duplex | 96875 | Mouse | In-vitro grade; in-vivo grade | Detail |
| pGMoligo716849 | Pre-made Cynomolgus/Rhesus macaque PRG4 siRNA oligo Duplex | 716849 | Cynomolgus/Rhesus macaque | In-vitro grade; in-vivo grade | Detail |
| pGMoligo101085684 | Pre-made Cat/Feline PRG4 siRNA oligo Duplex | 101085684 | Cat/Feline | In-vitro grade; in-vivo grade | Detail |
| pGMoligo664716 | Pre-made Dog/Canine PRG4 siRNA oligo Duplex | 664716 | Dog/Canine | In-vitro grade; in-vivo grade | Detail |
| pGMoligo280867 | Pre-made Bovines/Cattle PRG4/MSF/lubricin siRNA oligo Duplex | 280867 | Bovines/Cattle | In-vitro grade; in-vivo grade | Detail |
| pGMoligo100034016 | Pre-made Equine/Horse PRG4 siRNA oligo Duplex | 100034016 | Equine/Horse | In-vitro grade; in-vivo grade | Detail |
PRG4 antibody/GMab
| Cat No. | Species | Antibody Name | Format | Classified by tag | Detail |
|---|
| GM-Tg-hg-T94942-Ab | Human | Anti-Human PRG4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-rg-T94942-Ab | Rat | Anti-Rat PRG4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-mg-T94942-Ab | Mouse | Anti-Mouse PRG4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cynog-T94942-Ab | Cynomolgus/Rhesus macaque | Anti-Cynomolgus/Rhesus macaque PRG4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-felg-T94942-Ab | Cat/Feline | Anti-Cat/Feline PRG4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-cang-T94942-Ab | Dog/Canine | Anti-Dog/Canine PRG4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-bovg-T94942-Ab | Bovines/Cattle | Anti-Bovines/Cattle PRG4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
| GM-Tg-equg-T94942-Ab | Equine/Horse | Anti-Equine/Horse PRG4 monoclonal antibody | mab | FACS/Biofunctional Antibody, Therapeutics Target antibody | Detail |
PRG4 recombinant protein
| Cat No. | Species | Antigen Name | Expression Platform | Detail |
|---|
| GM-Tg-hg-T94942-Ag | Human | Human PRG4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-rg-T94942-Ag | Rat | Rat PRG4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-mg-T94942-Ag | Mouse | Mouse PRG4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cynog-T94942-Ag | Cynomolgus/Rhesus macaque | Cynomolgus/Rhesus macaque PRG4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-felg-T94942-Ag | Cat/Feline | Cat/Feline PRG4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-cang-T94942-Ag | Dog/Canine | Dog/Canine PRG4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-bovg-T94942-Ag | Bovines/Cattle | Bovines/Cattle PRG4 recombinant protein | Mammalian cell | Detail |
| GM-Tg-equg-T94942-Ag | Equine/Horse | Equine/Horse PRG4 recombinant protein | Mammalian cell | Detail |
