Recombinant multi-species Caspase 9/p35/p10/CASP9 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Caspase 9/p35/p10/CASP9 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
The Alternative Names of target: APAF-3,APAF3,Apaf3,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3 (APAF-3),CASP-9,CASP9,Casp-9-CTD,Casp9,Casp9_v1,Caspase 9,Caspase-9,ICE-LAP6,ICE-like apoptotic protease 6 (ICE-LAP6),Ice-Lap6,MCH6,Mch6,PPP1R56,p10,p35

Target products collectionGo to Caspase 9/p35/p10/CASP9 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

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Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T93903-Ag-1/ GM-Tg-hg-T93903-Ag-2 Human Caspase 9/p35/p10/CASP9 protein Human
GM-Tg-rg-T93903-Ag-1/ GM-Tg-rg-T93903-Ag-2 Rat Caspase 9/p35/p10/CASP9 protein Rat
GM-Tg-mg-T93903-Ag-1/ GM-Tg-mg-T93903-Ag-2 Mouse Caspase 9/p35/p10/CASP9 protein Mouse
GM-Tg-cynog-T93903-Ag-1/ GM-Tg-cynog-T93903-Ag-2 Cynomolgus/Rhesus macaque Caspase 9/p35/p10/CASP9 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T93903-Ag-1/ GM-Tg-felg-T93903-Ag-2 Feline Caspase 9/p35/p10/CASP9 protein Feline
GM-Tg-cang-T93903-Ag-1/ GM-Tg-cang-T93903-Ag-2 Canine Caspase 9/p35/p10/CASP9 protein Canine
GM-Tg-bovg-T93903-Ag-1/ GM-Tg-bovg-T93903-Ag-2 Bovine Caspase 9/p35/p10/CASP9 protein Bovine
GM-Tg-equg-T93903-Ag-1/ GM-Tg-equg-T93903-Ag-2 Equine Caspase 9/p35/p10/CASP9 protein Equine

Size： 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T93903-Ag-1/ GM-Tg-hg-T93903-Ag-2; GM-Tg-rg-T93903-Ag-1/ GM-Tg-rg-T93903-Ag-2;
GM-Tg-mg-T93903-Ag-1/ GM-Tg-mg-T93903-Ag-2; GM-Tg-cynog-T93903-Ag-1/ GM-Tg-cynog-T93903-Ag-2;
GM-Tg-felg-T93903-Ag-1/ GM-Tg-felg-T93903-Ag-2; GM-Tg-cang-T93903-Ag-1/ GM-Tg-cang-T93903-Ag-2;
GM-Tg-bovg-T93903-Ag-1/ GM-Tg-bovg-T93903-Ag-2; GM-Tg-equg-T93903-Ag-1/ GM-Tg-equg-T93903-Ag-2
Products Name Caspase 9/p35/p10/CASP9 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name Caspase 9/p35/p10/CASP9
Protein Sub-location Introcelluar Protein
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Caspase 9/p35/p10/CASP9 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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