Caspase 9/p35/p10/CASP9 Target & Gene Products-cDNA ORF clones/siRNA/antibody/protein

Explore Caspase 9/p35/p10/CASP9 gene products and cross-species research data at TarMart platform. Discover comprehensive biological information, expression tools, and therapeutic insights for Homo sapiens (human), Cynomolgus monkeys, rodents (mouse/rat), canines, felines, bovines, and equines. Your premier destination for multi-species gene research solutions
Target sublocation: Introcelluar Protein.
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

Target ID	GM-T93903
Target Name	Caspase 9/p35/p10/CASP9
Gene Group ldentifer （Target Gene ID in Homo species)	842
Gene ID	100054331 (Equus caballus), 100140945 (Bos taurus), 12371 (Mus musculus), 487432 (Canis lupus familiaris) 58918 (Rattus norvegicus), 694544 (Macaca mulatta), 768260 (Felis catus), 842 (Homo sapiens)
Target Alternative Names	APAF-3,APAF3,Apaf3,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3 (APAF-3),CASP-9,CASP9,Casp-9-CTD,Casp9,Casp9_v1,Caspase 9,Caspase-9,ICE-LAP6,ICE-like apoptotic protease 6 (ICE-LAP6),Ice-Lap6,MCH6,Mch6,PPP1R56,p10,p35
Uniprot Accession	Q8C3Q9,P55211
Protein Sub-location	Introcelluar Protein
Category	Therapeutics Target
Disease	cancer
Disease from KEGG	p53 signaling pathway, PI3K-Akt signaling pathway, Apoptosis, Apoptosis - multiple species, Thyroid hormone signaling pathway, Alzheimer disease, Pathogenic Escherichia coli infection, Legionellosis, Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Human cytomegalovirus infection, Influenza A, Kaposi sarcoma-associated herpesvirus infection, Epstein-Barr virus infection, Pathways in cancer, Colorectal cancer, Pancreatic cancer, Endometrial cancer, Prostate cancer, Small cell lung cancer, Non-small cell lung cancer, Viral myocarditis, Lipid and atherosclerosis
Gene Ensembl	ENSECAG00000017291, ENSBTAG00000002472, ENSMUSG00000028914, ENSCAFG00845000379, ENSMMUG00000018163, ENSG00000132906
Target Classification	Tumor-associated antigen (TAA)

Pre-made viral vector of Caspase 9/p35/p10/CASP9 cDNA Clones/ORF Plasmid

Cat No.	Product Name	NMID	GeneID	Species	Type	Marker	Fusion Tag	Promoter	Detail
pGMLP003199	Human CASP9/APAF-3/APAF3 Lentivirus plasmid	NM_001229	842	Human	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
pGMAP000333	Human CASP9/APAF-3/APAF3 Adenovirus plasmid	BC002452	842	Human	Adenovirus plasmid	GFP	3xflag (C-Terminal)	EF1	Detail
vGMLP003199	Human CASP9/APAF-3/APAF3 Lentivirus particle	NM_001229	842	Human	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMAP000333	Human CASP9/APAF-3/APAF3 Adenovirus particle	BC002452	842	Human	Adenovirus particle	GFP	3xflag (C-Terminal)	EF1	Detail
pGMAD000354	Rat Casp9/Apaf3/Casp-9-CTD Adenovirus plasmid	NM_031632.1	58918	Rat	Adenovirus plasmid	GFP	3xflag (C-Terminal)	EF1	Detail
vGMAD000354	Rat Casp9/Apaf3/Casp-9-CTD Adenovirus particle	NM_031632.1	58918	Rat	Adenovirus particle	GFP	3xflag (C-Terminal)	EF1	Detail
pGMLPm004983	Mouse Casp9/AI115399/APAF-3 Lentivirus plasmid	NM_015733.5	12371	Mouse	Lentivirus plasmid	ZsGreen	3xflag (C-Terminal)	CMV	Detail
vGMLPm004983	Mouse Casp9/AI115399/APAF-3 Lentivirus particle	NM_015733.5	12371	Mouse	Lentivirus particle	ZsGreen	3xflag (C-Terminal)	CMV	Detail

Caspase 9/p35/p10/CASP9 siRNA/miRNA/oligo for RNA interfence (RNAi)

Cat No.	Product Name	GeneID	Species	Grade	Detail
pGMoligo842	Pre-made Human CASP9/MCH6/APAF3 siRNA oligo Duplex	842	Human	In-vitro grade; in-vivo grade	Detail
pGMoligo58918	Pre-made Rat Casp9/Mch6/Apaf3 siRNA oligo Duplex	58918	Rat	In-vitro grade; in-vivo grade	Detail
pGMoligo12371	Pre-made Mouse Casp9/Mch6/APAF-3 siRNA oligo Duplex	12371	Mouse	In-vitro grade; in-vivo grade	Detail
pGMoligo694544	Pre-made Cynomolgus/Rhesus macaque CASP9 siRNA oligo Duplex	694544	Cynomolgus/Rhesus macaque	In-vitro grade; in-vivo grade	Detail
pGMoligo768260	Pre-made Cat/Feline CASP9 siRNA oligo Duplex	768260	Cat/Feline	In-vitro grade; in-vivo grade	Detail
pGMoligo487432	Pre-made Dog/Canine CASP9/ICE-LAP6 siRNA oligo Duplex	487432	Dog/Canine	In-vitro grade; in-vivo grade	Detail
pGMoligo100140945	Pre-made Bovines/Cattle CASP9 siRNA oligo Duplex	100140945	Bovines/Cattle	In-vitro grade; in-vivo grade	Detail
pGMoligo100054331	Pre-made Equine/Horse CASP9 siRNA oligo Duplex	100054331	Equine/Horse	In-vitro grade; in-vivo grade	Detail

Caspase 9/p35/p10/CASP9 antibody/GMab

Cat No.	Species	Antibody Name	Format	Classified by tag	Detail
GM-Tg-hg-T93903-Ab	Human	Anti-Human Caspase 9/p35/p10/CASP9 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-rg-T93903-Ab	Rat	Anti-Rat Caspase 9/p35/p10/CASP9 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-mg-T93903-Ab	Mouse	Anti-Mouse Caspase 9/p35/p10/CASP9 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-cynog-T93903-Ab	Cynomolgus/Rhesus macaque	Anti-Cynomolgus/Rhesus macaque Caspase 9/p35/p10/CASP9 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-felg-T93903-Ab	Cat/Feline	Anti-Cat/Feline Caspase 9/p35/p10/CASP9 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-cang-T93903-Ab	Dog/Canine	Anti-Dog/Canine Caspase 9/p35/p10/CASP9 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-bovg-T93903-Ab	Bovines/Cattle	Anti-Bovines/Cattle Caspase 9/p35/p10/CASP9 monoclonal antibody	mab	Therapeutics Target antibody	Detail
GM-Tg-equg-T93903-Ab	Equine/Horse	Anti-Equine/Horse Caspase 9/p35/p10/CASP9 monoclonal antibody	mab	Therapeutics Target antibody	Detail

Caspase 9/p35/p10/CASP9 recombinant protein

Cat No.	Species	Antigen Name	Expression Platform	Detail
GM-Tg-hg-T93903-Ag	Human	Human Caspase 9/p35/p10/CASP9 recombinant protein	Mammalian cell	Detail
GM-Tg-rg-T93903-Ag	Rat	Rat Caspase 9/p35/p10/CASP9 recombinant protein	Mammalian cell	Detail
GM-Tg-mg-T93903-Ag	Mouse	Mouse Caspase 9/p35/p10/CASP9 recombinant protein	Mammalian cell	Detail
GM-Tg-cynog-T93903-Ag	Cynomolgus/Rhesus macaque	Cynomolgus/Rhesus macaque Caspase 9/p35/p10/CASP9 recombinant protein	Mammalian cell	Detail
GM-Tg-felg-T93903-Ag	Cat/Feline	Cat/Feline Caspase 9/p35/p10/CASP9 recombinant protein	Mammalian cell	Detail
GM-Tg-cang-T93903-Ag	Dog/Canine	Dog/Canine Caspase 9/p35/p10/CASP9 recombinant protein	Mammalian cell	Detail
GM-Tg-bovg-T93903-Ag	Bovines/Cattle	Bovines/Cattle Caspase 9/p35/p10/CASP9 recombinant protein	Mammalian cell	Detail
GM-Tg-equg-T93903-Ag	Equine/Horse	Equine/Horse Caspase 9/p35/p10/CASP9 recombinant protein	Mammalian cell	Detail