Recombinant multi-species CCL21 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCL21 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Sep 2014]
The Alternative Names of target: 6CKBAC2,6Ckine,ALP,Beta-chemokine exodus-2,C-C motif chemokine 21,CCL21,CKb9,Ccl21,Ccl21a,Ccl21b,ECL,Gm1987,SCYA21,SCYA21a,SLC,Scya21,Scya21b,Secondary lymphoid-tissue chemokine (SLC),Small-inducible cytokine A21,TCA4,Tca4,plt
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T93237-Ag-1/ GM-Tg-hg-T93237-Ag-2 | Human CCL21 protein | Human |
| GM-Tg-rg-T93237-Ag-1/ GM-Tg-rg-T93237-Ag-2 | Rat CCL21 protein | Rat |
| GM-Tg-mg-T93237-Ag-1/ GM-Tg-mg-T93237-Ag-2 | Mouse CCL21 protein | Mouse |
| GM-Tg-cynog-T93237-Ag-1/ GM-Tg-cynog-T93237-Ag-2 | Cynomolgus/Rhesus macaque CCL21 protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T93237-Ag-1/ GM-Tg-felg-T93237-Ag-2 | Feline CCL21 protein | Feline |
| GM-Tg-cang-T93237-Ag-1/ GM-Tg-cang-T93237-Ag-2 | Canine CCL21 protein | Canine |
| GM-Tg-bovg-T93237-Ag-1/ GM-Tg-bovg-T93237-Ag-2 | Bovine CCL21 protein | Bovine |
| GM-Tg-equg-T93237-Ag-1/ GM-Tg-equg-T93237-Ag-2 | Equine CCL21 protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T93237-Ag-1/ GM-Tg-hg-T93237-Ag-2;
GM-Tg-rg-T93237-Ag-1/ GM-Tg-rg-T93237-Ag-2;
GM-Tg-mg-T93237-Ag-1/ GM-Tg-mg-T93237-Ag-2; GM-Tg-cynog-T93237-Ag-1/ GM-Tg-cynog-T93237-Ag-2; GM-Tg-felg-T93237-Ag-1/ GM-Tg-felg-T93237-Ag-2; GM-Tg-cang-T93237-Ag-1/ GM-Tg-cang-T93237-Ag-2; GM-Tg-bovg-T93237-Ag-1/ GM-Tg-bovg-T93237-Ag-2; GM-Tg-equg-T93237-Ag-1/ GM-Tg-equg-T93237-Ag-2 |
| Products Name | CCL21 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | CCL21 |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCL21 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.