Recombinant multi-species CCL21 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCL21 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Sep 2014]
The Alternative Names of target: 6CKBAC2,6Ckine,ALP,Beta-chemokine exodus-2,C-C motif chemokine 21,CCL21,CKb9,Ccl21,Ccl21a,Ccl21b,ECL,Gm1987,SCYA21,SCYA21a,SLC,Scya21,Scya21b,Secondary lymphoid-tissue chemokine (SLC),Small-inducible cytokine A21,TCA4,Tca4,plt

Target products collectionGo to CCL21 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)


Product information

Catalog No. Product Name Species Reactivity
GM-Tg-hg-T93237-Ag-1/ GM-Tg-hg-T93237-Ag-2 Human CCL21 protein Human
GM-Tg-rg-T93237-Ag-1/ GM-Tg-rg-T93237-Ag-2 Rat CCL21 protein Rat
GM-Tg-mg-T93237-Ag-1/ GM-Tg-mg-T93237-Ag-2 Mouse CCL21 protein Mouse
GM-Tg-cynog-T93237-Ag-1/ GM-Tg-cynog-T93237-Ag-2 Cynomolgus/Rhesus macaque CCL21 protein Cynomolgus/ Rhesus macaque
GM-Tg-felg-T93237-Ag-1/ GM-Tg-felg-T93237-Ag-2 Feline CCL21 protein Feline
GM-Tg-cang-T93237-Ag-1/ GM-Tg-cang-T93237-Ag-2 Canine CCL21 protein Canine
GM-Tg-bovg-T93237-Ag-1/ GM-Tg-bovg-T93237-Ag-2 Bovine CCL21 protein Bovine
GM-Tg-equg-T93237-Ag-1/ GM-Tg-equg-T93237-Ag-2 Equine CCL21 protein Equine

Size: 1mg | 10mg | 100mg



Product Description

Catalog No. GM-Tg-hg-T93237-Ag-1/ GM-Tg-hg-T93237-Ag-2; GM-Tg-rg-T93237-Ag-1/ GM-Tg-rg-T93237-Ag-2;
GM-Tg-mg-T93237-Ag-1/ GM-Tg-mg-T93237-Ag-2; GM-Tg-cynog-T93237-Ag-1/ GM-Tg-cynog-T93237-Ag-2;
GM-Tg-felg-T93237-Ag-1/ GM-Tg-felg-T93237-Ag-2; GM-Tg-cang-T93237-Ag-1/ GM-Tg-cang-T93237-Ag-2;
GM-Tg-bovg-T93237-Ag-1/ GM-Tg-bovg-T93237-Ag-2; GM-Tg-equg-T93237-Ag-1/ GM-Tg-equg-T93237-Ag-2
Products Name CCL21 protein
Species Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name CCL21
Protein Sub-location Secreted Protein/Potential Cytokines
Isotypes Recombinant protein
Expression platform Mammalian cell
Bioactivity validation Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag His
Products description Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CCL21 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity Purity: ≥95% (SDS-PAGE)
Application In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference






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    GMab, developed by GeneMedi, constitutes an advanced library of recombinant monoclonal antibodies, each meticulously designed to target specific molecular entities. Leveraging the sophisticated capabilities of GM’s Taurus™ and LIBRA™ platforms, GMab synthesizes antibodies characterized by high binding affinity, exceptional physicochemical stability, and optimal developability profiles.
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