Recombinant multi-species Amphiregulin/AREG protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Amphiregulin/AREG protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]
The Alternative Names of target: AR,AREG,AREGB,Amphiregulin,Areg,CRDGF,Colorectum cell-derived growth factor (CRDGF),Mcub,SDGF,Sdgf
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Product information
| Catalog No. | Product Name | Species Reactivity |
|---|---|---|
| GM-Tg-hg-T92834-Ag-1/ GM-Tg-hg-T92834-Ag-2 | Human Amphiregulin/AREG protein | Human |
| GM-Tg-rg-T92834-Ag-1/ GM-Tg-rg-T92834-Ag-2 | Rat Amphiregulin/AREG protein | Rat |
| GM-Tg-mg-T92834-Ag-1/ GM-Tg-mg-T92834-Ag-2 | Mouse Amphiregulin/AREG protein | Mouse |
| GM-Tg-cynog-T92834-Ag-1/ GM-Tg-cynog-T92834-Ag-2 | Cynomolgus/Rhesus macaque Amphiregulin/AREG protein | Cynomolgus/ Rhesus macaque |
| GM-Tg-felg-T92834-Ag-1/ GM-Tg-felg-T92834-Ag-2 | Feline Amphiregulin/AREG protein | Feline |
| GM-Tg-cang-T92834-Ag-1/ GM-Tg-cang-T92834-Ag-2 | Canine Amphiregulin/AREG protein | Canine |
| GM-Tg-bovg-T92834-Ag-1/ GM-Tg-bovg-T92834-Ag-2 | Bovine Amphiregulin/AREG protein | Bovine |
| GM-Tg-equg-T92834-Ag-1/ GM-Tg-equg-T92834-Ag-2 | Equine Amphiregulin/AREG protein | Equine |
Size: 1mg | 10mg | 100mg
Product Description
| Catalog No. |
GM-Tg-hg-T92834-Ag-1/ GM-Tg-hg-T92834-Ag-2;
GM-Tg-rg-T92834-Ag-1/ GM-Tg-rg-T92834-Ag-2;
GM-Tg-mg-T92834-Ag-1/ GM-Tg-mg-T92834-Ag-2; GM-Tg-cynog-T92834-Ag-1/ GM-Tg-cynog-T92834-Ag-2; GM-Tg-felg-T92834-Ag-1/ GM-Tg-felg-T92834-Ag-2; GM-Tg-cang-T92834-Ag-1/ GM-Tg-cang-T92834-Ag-2; GM-Tg-bovg-T92834-Ag-1/ GM-Tg-bovg-T92834-Ag-2; GM-Tg-equg-T92834-Ag-1/ GM-Tg-equg-T92834-Ag-2 |
| Products Name | Amphiregulin/AREG protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | Amphiregulin/AREG |
| Protein Sub-location | Secreted Protein/Potential Cytokines |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine Amphiregulin/AREG protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution |
Lyophilized from GM's Protein Stability Buffer2
(PSB2,Confidential Ingredients) or PBS
(pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
About Gmab

GMab, developed by GeneMedi, constitutes an
advanced library of recombinant
monoclonal antibodies, each meticulously
designed to target specific molecular
entities. Leveraging the sophisticated
capabilities of GM’s Taurus™ and LIBRA™
platforms, GMab synthesizes antibodies
characterized by high binding affinity,
exceptional physicochemical stability, and
optimal developability profiles.
Through
expression in mammalian cell lines, GMab has
been established as a paradigmatic
reference antibody. It holds significance in
myriad domains of biological drug
discovery, encompassing cellular cultivation,
innovative assay methodologies,
strategic animal model systematization, in-depth
pharmacokinetic & pharmacodynamic
(PK/PD) modeling, and intricate mechanism of
action (MOA) investigations.